Blog
About

28
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      The TetO rat as a new translational model for type 2 diabetic retinopathy by inducible insulin receptor knockdown.

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Although the renin-angiotensin system plays an important role in the progression of diabetic retinopathy, its influence therein has not been systematically evaluated. Here we test the suitability of a new translational model of diabetic retinopathy, the TetO rat, for addressing the role of angiotensin-II receptor 1 (AT1) blockade in experimental diabetic retinopathy.

          Related collections

          Author and article information

          Journal
          Diabetologia
          Diabetologia
          Springer Nature
          1432-0428
          0012-186X
          Jan 2017
          : 60
          : 1
          Affiliations
          [1 ] Department of Ophthalmology, Charité-Universitätsmedizin Berlin Campus Virchow Klinikum, Augustenburger Platz 1, 13353, Berlin, Germany. nadine.reichhart@charite.de.
          [2 ] Department of Ophthalmology, Charité-Universitätsmedizin Berlin Campus Virchow Klinikum, Augustenburger Platz 1, 13353, Berlin, Germany.
          [3 ] Experimental and Clinical Research Center, a cooperation between the Max Delbrück Center for Molecular Medicine in the Helmholtz Association and the Charité-Universitätsmedizin Berlin, Berlin, Germany.
          [4 ] Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.
          [5 ] Berlin Institute of Health, Berlin, Germany.
          [6 ] Department of Obstetrics, Charité-Universitätsmedizin Berlin Campus Virchow Klinikum, Berlin, Germany.
          [7 ] Department of Gynecology, Charité-Universitätsmedizin Berlin Campus Virchow Klinikum, Berlin, Germany.
          [8 ] Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, MI, USA.
          [9 ] German Center for Cardiovascular Disease, Berlin, Germany.
          [10 ] Department of Biology, Universität zu Lübeck, Lübeck, Germany.
          [11 ] Charité-Universitätsmedizin Berlin Campus Berlin-Buch, Berlin, Germany.
          [12 ] Department of Cardiology and Nephrology, HELIOS Klinikum Berlin-Buch, Berlin, Germany.
          [13 ] Department of Ophthalmology, Charité-Universitätsmedizin Berlin Campus Virchow Klinikum, Augustenburger Platz 1, 13353, Berlin, Germany. antonia.joussen@charite.de.
          Article
          10.1007/s00125-016-4115-0
          10.1007/s00125-016-4115-0
          27704165

          Comments

          Comment on this article