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      Changes of Th17/Tc17 and Th17/Treg cells in endometrial carcinoma.

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          Abstract

          T helper 17 (Th17), T cytotoxic 17 (Tc17) and regulatory T (Treg) cells are important factors in the pathogenesis of inflammatory and autoimmune diseases. However, information concerning the roles of these cells in antitumor immunity or endometrial tumorigenesis remains limited. In this study, we aimed to describe the distribution of Th17, Tc17 and Treg cells in endometrial carcinoma patients, and elucidate the probable role of these effector T cells.

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          Author and article information

          Journal
          Gynecol. Oncol.
          Gynecologic oncology
          Elsevier BV
          1095-6859
          0090-8258
          Mar 2014
          : 132
          : 3
          Affiliations
          [1 ] Department of Obstetrics and Gynecology, Qilu Hospital, Shandong University, Jinan 250012, PR China; Key Laboratory of Gynecologic Oncology, Qilu Hospital, Shandong University, Jinan 250012, PR China.
          [2 ] Jinan Maternity and Children's Hospital, Jinan 250001, PR China.
          [3 ] People's Hospital of Weifang City, Weifang 262500, PR China.
          [4 ] Yantaishan Hospital, Yantai 264000, PR China.
          [5 ] Department of Obstetrics and Gynecology, Qilu Hospital, Shandong University, Jinan 250012, PR China; Hematology Oncology Center, Qilu Hospital, Shandong University, Jinan 250012, PR China.
          [6 ] Hematology Oncology Center, Qilu Hospital, Shandong University, Jinan 250012, PR China.
          [7 ] Department of Obstetrics and Gynecology, Qilu Hospital, Shandong University, Jinan 250012, PR China.
          [8 ] Department of Obstetrics and Gynecology, Qilu Hospital, Shandong University, Jinan 250012, PR China. Electronic address: cuibaoxia@sdu.edu.cn.
          Article
          S0090-8258(13)01427-3
          10.1016/j.ygyno.2013.12.036
          24388919
          61f13a34-32c1-4dee-86f8-096bb92bf3f9
          History

          Treg,Tumor immunity,Endometrial carcinoma,Tc17,Th17
          Treg, Tumor immunity, Endometrial carcinoma, Tc17, Th17

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