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      Artefacts in histopathology

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          Abstract

          Histopathology is the science of slide analysis for the diagnostic and research purposes. However, sometimes the presence of certain artefacts in a microscopic section can result in misinterpretations leading to diagnostic pitfalls that can result in increased patient morbidity. This article reviews the common artefacts encountered during slide examination alongside the remedial measures which can be undertaken to differentiate between an artefact and tissue constituent.

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          Artefacts in histopathology

          Elizabeth McInnes (2005)
          Article 0 comments Cited 16 times – based on 0 reviews     Review now
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            Artifacts in oral biopsy specimens.

            J Margarone, J R Natiella, C D Vaughan (1985)
            More than proper surgical technique is required to facilitate the proper diagnosis of an oral biopsy specimen. The proper preparation of the tissue for microscopic analysis depends on steps taken by the surgeon, assistant, and histotechnician to reduce the inclusion of artifacts. There are many ways that the exact interpretation of tissue specimens can be compromised. Unfortunately, many practitioners seem to be unaware of the extent of this problem, as well as how easily artifacts can be prevented.
            Article 0 comments Cited 7 times – based on 0 reviews     Review now
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              Artefacts created during oral biopsy procedures.

              G Ficarra, B. McClintock, L Hansen (1987)
              Biopsy specimens removed from the oral cavity are often small, and there is high potential for causing artefacts at several stages: during removal, fixation, embedding, or staining. This report describes several of the most common artefacts created by erroneous handling of oral tissue and lists recommendations for preventing them.
              Article 0 comments Cited 6 times – based on 0 reviews     Review now
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                Author and article information

                Journal
                Journal ID (nlm-ta): J Oral Maxillofac Pathol
                Journal ID (iso-abbrev): J Oral Maxillofac Pathol
                Journal ID (publisher-id): JOMFP
                Title: Journal of Oral and Maxillofacial Pathology : JOMFP
                Publisher: Medknow Publications & Media Pvt Ltd (India )
                ISSN (Print): 0973-029X
                ISSN (Electronic): 1998-393X
                Publication date (Print): September 2014
                Volume: 18
                Issue: Suppl 1
                Pages: S111-S116
                Affiliations
                [1] Department of Oral and Maxillofacial Pathology, MM College of Dental Sciences and Research, Maharishi Markandeshwar University, Mullana, Haryana, India
                Author notes
                Address for Correspondence: Dr. Shailja Chatterjee, Deparment of Oral and Maxillofacial Pathology, MM College of Dental Sciences and Research, Maharishi Markandeshwar University, Mullana - 133 207, Haryana, India. E-mail: shailjachatterjee@ 123456gmail.com
                Article
                Publisher ID: JOMFP-18-111
                DOI: 10.4103/0973-029X.141346
                PMC ID: 4211218
                PubMed ID: 25364159
                SO-VID: 622f0606-ab76-4188-a6a7-478717957cbb
                Copyright © Copyright: © Journal of Oral and Maxillofacial Pathology
                License:

                This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                Date received : 10 October 2012
                Date accepted : 04 September 2014
                Categories
                Subject: Review Article

                ScienceOpen disciplines: Pathology
                Keywords: artefacts,diagnostic pitfalls,histopathology,morbidity,mortality,remedies
                Data availability:
                ScienceOpen disciplines: Pathology
                Keywords: artefacts, diagnostic pitfalls, histopathology, morbidity, mortality, remedies

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