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      Expectations influence treatment outcomes in patients with low back pain. A secondary analysis of data from a randomized clinical trial

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          Abstract

          Background

          Low back pain (LBP) is a global public health challenge, which causes high healthcare costs and the highest burden on society in terms of years lived with disability. While patients’ expectations for improvement may have effects on LBP treatment outcomes, it remains unclear if psychological profiles modify this relationship. Therefore, the objectives of this study were to investigate if (a) patients’ expectations predicted short‐term outcome, and (b) psychological profile, pain intensity and self‐rated health modified the relationship between expectations and outcome.

          Methods

          Data were collected between April 2012 and January 2016 during the inclusion into a randomized controlled trial. Potentially eligible participants were identified through 40 chiropractic clinics located across Sweden. Patients’ expectations, psychological profile, pain intensity, activity limitation and self‐rated health were collected from patients with recurrent persistent LBP during their first chiropractic visit ( n = 593). Subjective improvement was measured at the fourth visit.

          Results

          Patients with a high expectation of improvement had 58% higher risk to report an improvement at the fourth visit (RR = 1.58, 95% CI: 1.28, 1.95). Controlling for potential confounders only slightly decreased the strength of this association (RR = 1.49, 95% CI: 1.20, 1.86). Baseline pain intensity, psychological profile and self‐rated health did not modify the effect of expectation on outcome.

          Conclusions

          Baseline patients’ expectations play an important role when predicting LBP treatment outcomes. Clinicians should consider and address patients’ expectations at the first visit to best inform prognosis.

          Significance

          This study confirms the importance of patients’ expectations in a clinical setting. Patients’ expectations predict the short‐term outcome of chiropractic care for LBP. Pain intensity, psychological profile and self‐rated health did not modify this relationship.

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          Most cited references52

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          The West Haven-Yale Multidimensional Pain Inventory (WHYMPI).

          The complexity of chronic pain has represented a major dilemma for clinical researchers interested in the reliable and valid assessment of the problem and the evaluation of treatment approaches. The West Haven-Yale Multidimensional Pain Inventory (WHYMPI) was developed in order to fill a widely recognized void in the assessment of clinical pain. Assets of the inventory are its brevity and clarity, its foundation in contemporary psychological theory, its multidimensional focus, and its strong psychometric properties. Three parts of the inventory, comprised of 12 scales, examine the impact of pain on the patients' lives, the responses of others to the patients' communications of pain, and the extent to which patients participate in common daily activities. The instrument is recommended for use in conjunction with behavioral and psychophysiological assessment strategies in the evaluation of chronic pain patients in clinical settings. The utility of the WHYMPI in empirical investigations of chronic pain is also discussed.
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            A review of psychological risk factors in back and neck pain.

            S J Linton (2000)
            The literature on psychological factors in neck and back pain was systematically searched and reviewed. To summarize current knowledge concerning the role of psychological variables in the etiology and development of neck and back pain. Recent conceptions of spinal pain, especially chronic back pain, have highlighted the role of psychological factors. Numerous studies subsequently have examined the effects of various psychological factors in neck and back pain. There is a need to review this material to ascertain what conclusions may be drawn. Medical and psychological databases and cross-referencing were used to locate 913 potentially relevant articles. A table of 37 studies was constructed, consisting only of studies with prospective designs to ensure quality. Each study was reviewed for the population studied, the psychological predictor variables, and the outcome. The available literature indicated a clear link between psychological variables and neck and back pain. The prospective studies indicated that psychological variables were related to the onset of pain, and to acute, subacute, and chronic pain. Stress, distress, or anxiety as well as mood and emotions, cognitive functioning, and pain behavior all were found to be significant factors. Personality factors produced mixed results. Although the level of evidence was low, abuse also was found to be a potentially significant factor. Psychological factors play a significant role not only in chronic pain, but also in the etiology of acute pain, particularly in the transition to chronic problems. Specific types of psychological variables emerge and may be important in distinct developmental time frames, also implying that assessment and intervention need to reflect these variables. Still, psychological factors account for only a portion of the variance, thereby highlighting the multidimensional view. Because the methodologic quality of the studies varied considerably, future research should focus on improving quality and addressing new questions such as the mechanism, the developmental time factor, and the relevance that these risk factors have for intervention.
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              A consensus approach toward the standardization of back pain definitions for use in prevalence studies.

              A modified Delphi study conducted with 28 experts in back pain research from 12 countries. To identify standardized definitions of low back pain that could be consistently used by investigators in prevalence studies to provide comparable data. Differences in the definition of back pain prevalence in population studies lead to heterogeneity in study findings, and limitations or impossibilities in comparing or summarizing prevalence figures from different studies. Back pain definitions were identified from 51 articles reporting population-based prevalence studies, and dissected into 77 items documenting 7 elements. These items were submitted to a panel of experts for rating and reduction, in 3 rounds (participation: 76%). Preliminary results were presented and discussed during the Amsterdam Forum VIII for Primary Care Research on Low Back Pain, compared with scientific evidence and confirmed and fine-tuned by the panel in a fourth round and the preparation of the current article. Two definitions were agreed on a minimal definition (with 1 question covering site of low back pain, symptoms observed, and time frame of the measure, and a second question on severity of low back pain) and an optimal definition that is made from the minimal definition and add-ons (covering frequency and duration of symptoms, an additional measure of severity, sciatica, and exclusions) that can be adapted to different needs. These definitions provide standards that may improve future comparisons of low back pain prevalence figures by person, place and time characteristics, and offer opportunities for statistical summaries.
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                Author and article information

                Contributors
                andreas.eklund@ki.se
                Journal
                Eur J Pain
                Eur J Pain
                10.1002/(ISSN)1532-2149
                EJP
                European Journal of Pain (London, England)
                John Wiley and Sons Inc. (Hoboken )
                1090-3801
                1532-2149
                20 May 2019
                August 2019
                : 23
                : 7 ( doiID: 10.1002/ejp.2019.23.issue-7 )
                : 1378-1389
                Affiliations
                [ 1 ] Unit of Intervention and Implementation Research for Worker Health The Institute of Environmental Medicine, Karolinska Institutet Stockholm Sweden
                [ 2 ] Discipline of Medicine, Faculty of Medicine Memorial University of Newfoundland St. John's Newfoundland and Labrador Canada
                [ 3 ] Department of Anatomy Université du Québec à Trois‐Rivières Trois‐Rivières Québec Canada
                [ 4 ] Department of Rehabilitation Sciences The Hong Kong Polytechnic University Hong Kong SAR China
                [ 5 ] Department of Sports Science and Clinical Biomechanics University of Southern Denmark Odense Denmark
                [ 6 ] National Research Centre for the Working Environment Copenhagen Denmark
                [ 7 ] Research Institute Parker University Dallas Texas
                [ 8 ] Nordic Institute of Chiropractic and Clinical Biomechanics Odense Denmark
                [ 9 ] Department of Chiropractic, Faculty of Science and Engineering Macquarie University Sydney Australia
                [ 10 ] Institute for Musculoskeletal Health, School of Public Health University of Sydney Sydney Australia
                Author notes
                [*] [* ] Correspondence

                Andreas Eklund, Unit of Intervention and Implementation Research for Worker Health, The Institute of Environmental Medicine (IMM), Karolinska Institutet, Nobels väg 13, 171 77 Stockholm, Sweden

                Email: andreas.eklund@ 123456ki.se

                Article
                EJP1407
                10.1002/ejp.1407
                6767754
                31034102
                6246e4a6-3fa2-47d4-b660-1b5512b213e8
                © 2019 The Authors. European Journal of Pain published by John Wiley & Sons Ltd on behalf of European Pain Federation ‐ EFIC®

                This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

                History
                : 02 May 2018
                : 09 April 2019
                : 17 April 2019
                Page count
                Figures: 3, Tables: 4, Pages: 12, Words: 8073
                Categories
                Original Article
                Original Articles
                Custom metadata
                2.0
                ejp1407
                August 2019
                Converter:WILEY_ML3GV2_TO_NLMPMC version:5.6.9 mode:remove_FC converted:30.09.2019

                Anesthesiology & Pain management
                Anesthesiology & Pain management

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