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      Type 1 diabetes.

      1 , 2 , 2
      Lancet (London, England)
      Elsevier BV

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          Abstract

          Over the past decade, knowledge of the pathogenesis and natural history of type 1 diabetes has grown substantially, particularly with regard to disease prediction and heterogeneity, pancreatic pathology, and epidemiology. Technological improvements in insulin pumps and continuous glucose monitors help patients with type 1 diabetes manage the challenge of lifelong insulin administration. Agents that show promise for averting debilitating disease-associated complications have also been identified. However, despite broad organisational, intellectual, and fiscal investments, no means for preventing or curing type 1 diabetes exists, and, globally, the quality of diabetes management remains uneven. This Seminar discusses current progress in epidemiology, pathology, diagnosis, and treatment of type 1 diabetes, and prospects for an improved future for individuals with this disease.

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          Author and article information

          Journal
          Lancet
          Lancet (London, England)
          Elsevier BV
          1474-547X
          0140-6736
          Jan 04 2014
          : 383
          : 9911
          Affiliations
          [1 ] Department of Pathology and Department of Pediatrics, University of Florida, Gainesville, FL, USA. Electronic address: atkinson@ufl.edu.
          [2 ] Barbara Davis Center for Childhood Diabetes, Aurora, CO, USA.
          Article
          NIHMS671875 S0140-6736(13)60591-7
          10.1016/S0140-6736(13)60591-7
          4380133
          23890997
          6311fc2b-7cc9-46ea-8921-baa91355e039
          Copyright © 2014 Elsevier Ltd. All rights reserved.
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