5
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: not found
      • Article: not found

      Bacterioruberin extracts from a genetically modified hyperpigmented Haloferax volcanii strain: antioxidant activity and bioactive properties on sperm cells

      Read this article at

      ScienceOpenPublisher
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Related collections

          Most cited references 51

          • Record: found
          • Abstract: found
          • Article: not found

          Radical scavenging ability of polyphenolic compounds towards DPPH free radical.

          Free radical scavenging activity of different polyphenolic compounds commonly present in wine has been evaluated using DPPH method. The experiments were performed with different amounts of phenols within the linear interval of response and with an excess of DPPH in all cases. In these conditions, for most of the compounds tested, the reaction was biphasic. Total stoichiometry values n confirm the implication of more than one step in the process. Flavan-3-ol compounds showed the highest values, especially procyanidins B1 (9.8) and B2 (9.1). In this family, n values coincide with the number of hydroxyl groups available. EC(50) and TEC(50) parameters have been calculated. EC(50) values are extremely diverse, being the procyanidins B1 and B2 the most potent scavenging compounds and resveratrol the less one. TEC(50) considers the rate of reaction towards the free radical. (+)-Catechin and (-)-epicatechin are the phenolic compounds that need more time to react. In contrast, caftaric and caffeic acids are the phenolic acids that react more rapidly. Antioxidant efficacy (AE) is a parameter that combines both factors. Compounds as kaempferol, with a high EC(50) value, could be considered as an antioxidant with low relevance, but instead shows the highest AE value of the phenolic compounds tested, due to its fast rate of reaction, what is of great biological importance.
            Bookmark
            • Record: found
            • Abstract: not found
            • Article: not found

            Carotenoids as membrane stabilizers in chloroplasts

             Michel Havaux (1998)
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Carotenoids: biochemistry, pharmacology and treatment.

              Carotenoids and retinoids have several similar biological activities such as antioxidant properties, the inhibition of malignant tumour growth and the induction of apoptosis. Supplementation with carotenoids can affect cell growth and modulate gene expression and immune responses. Epidemiological studies have shown a correlation between a high carotenoid intake in the diet with a reduced risk of breast, cervical, ovarian, colorectal cancers, and cardiovascular and eye diseases. Cancer chemoprevention by dietary carotenoids involves several mechanisms, including effects on gap junctional intercellular communication, growth factor signalling, cell cycle progression, differentiation-related proteins, retinoid-like receptors, antioxidant response element, nuclear receptors, AP-1 transcriptional complex, the Wnt/β-catenin pathway and inflammatory cytokines. Moreover, carotenoids can stimulate the proliferation of B- and T-lymphocytes, the activity of macrophages and cytotoxic T-cells, effector T-cell function and the production of cytokines. Recently, the beneficial effects of carotenoid-rich vegetables and fruits in health and in decreasing the risk of certain diseases has been attributed to the major carotenoids, β-carotene, lycopene, lutein, zeaxanthin, crocin (/crocetin) and curcumin, due to their antioxidant effects. It is thought that carotenoids act in a time- and dose-dependent manner. In this review, we briefly describe the biological and immunological activities of the main carotenoids used for the treatment of various diseases and their possible mechanisms of action.
                Bookmark

                Author and article information

                Journal
                Journal of Applied Microbiology
                J Appl Microbiol
                Wiley
                13645072
                March 2019
                March 2019
                January 02 2019
                : 126
                : 3
                : 796-810
                Affiliations
                [1 ]Instituto de Investigaciones Biológicas; FCEyN; Universidad Nacional de Mar del Plata (UNMDP); Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET); Mar del Plata Argentina
                [2 ]Departamento de Química; FCEyN (UNMDP); Mar del Plata Argentina
                [3 ]IFIMAR; Instituto de Investigaciones Físicas de Mar del Plata (CONICET-UNMDP); Mar del Plata Argentina
                [4 ]SaBio IREC (CSIC-UCLM-JCCM). ETSIAM. Campus Universitario; Albacete Spain
                Article
                10.1111/jam.14160
                © 2019

                Comments

                Comment on this article