Effects of Serotonin and Angiotensin on Testicular Blood Vessels in the Rat

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Abstract

The effect of serotonin and angiotensin on the testicular and epididymal blood vessels in the rat was demonstrated by in vivo angiography, using thorium dioxide as contrast substance. Doses of 10 mg/kg and 25 mg/kg serotonin caused vasoconstriction and temporary total occlusion of the testicular blood flow, respectively. Angiotensin caused only vasoconstriction and not total occlusion of the circulation. This experiment shows that serotonin is able to induce severe ischaemia in the rat testis.

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Journal

Journal ID (publisher-id): JVR

Journal ID (nlm-ta): J Vasc Res

Journal ID (doi): 10.1159/issn.1018-1172

Title: Journal of Vascular Research

Publisher: S. Karger AG

ISSN (Print): 1018-1172

ISSN (Electronic): 1423-0135

Publication date Subscription-year: 1970

Publication date (Print): 1970

Publication date (Electronic): 18 September 2008

Volume: 7

Issue: 5

Pages: 291-295

Affiliations

Institute of Roentgen Diagnostics, University Central Hospital, Helsinki

Article

Publisher ID: 157843 Other ID: Angiologica 1970;7:291–295

DOI: 10.1159/000157843

SO-VID: 6331e8af-320d-4090-85f3-5088bc8d83b7

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Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

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Pages: 5

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