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      Sex and Gender Equity in Research: rationale for the SAGER guidelines and recommended use

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          Abstract

          Background

          Sex and gender differences are often overlooked in research design, study implementation and scientific reporting, as well as in general science communication. This oversight limits the generalizability of research findings and their applicability to clinical practice, in particular for women but also for men. This article describes the rationale for an international set of guidelines to encourage a more systematic approach to the reporting of sex and gender in research across disciplines.

          Methods

          A panel of 13 experts representing nine countries developed the guidelines through a series of teleconferences, conference presentations and a 2-day workshop. An internet survey of 716 journal editors, scientists and other members of the international publishing community was conducted as well as a literature search on sex and gender policies in scientific publishing.

          Results

          The Sex and Gender Equity in Research (SAGER) guidelines are a comprehensive procedure for reporting of sex and gender information in study design, data analyses, results and interpretation of findings.

          Conclusions

          The SAGER guidelines are designed primarily to guide authors in preparing their manuscripts, but they are also useful for editors, as gatekeepers of science, to integrate assessment of sex and gender into all manuscripts as an integral part of the editorial process.

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          Most cited references16

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          CONSORT 2010 statement: updated guidelines for reporting parallel group randomized trials.

          The CONSORT (Consolidated Standards of Reporting Trials) statement is used worldwide to improve the reporting of randomized, controlled trials. Schulz and colleagues describe the latest version, CONSORT 2010, which updates the reporting guideline based on new methodological evidence and accumulating experience.
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            Studying sex and gender differences in pain and analgesia: a consensus report.

            In September 2006, members of the Sex, Gender and Pain Special Interest Group of the International Association for the Study of Pain met to discuss the following: (1) what is known about sex and gender differences in pain and analgesia; (2) what are the "best practice" guidelines for pain research with respect to sex and gender; and (3) what are the crucial questions to address in the near future? The resulting consensus presented herein includes input from basic science, clinical and psychosocial pain researchers, as well as from recognized experts in sexual differentiation and reproductive endocrinology. We intend this document to serve as a utilitarian and thought-provoking guide for future research on sex and gender differences in pain and analgesia, both for those currently working in this field as well as those still wondering, "Do I really need to study females?"
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              • Article: not found

              Inclusion, Analysis, and Reporting of Sex and Race/Ethnicity in Clinical Trials: Have We Made Progress?

              The National Institutes of Health (NIH) Revitalization Act of 1993 requires that NIH-funded clinical trials include women and minorities as participants; other federal agencies have adopted similar guidelines. The objective of this study is to determine the current level of compliance with these guidelines for the inclusion, analysis, and reporting of sex and race/ethnicity in federally funded randomized controlled trials (RCTs) and to compare the current level of compliance with that from 2004, which was reported previously.
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                Author and article information

                Contributors
                sheidari@rhmjournal.org.uk
                babor@uchc.edu
                Journal
                Res Integr Peer Rev
                Res Integr Peer Rev
                Research Integrity and Peer Review
                BioMed Central (London )
                2058-8615
                3 May 2016
                3 May 2016
                2016
                : 1
                : 2
                Affiliations
                [1 ]EASE Gender Policy Committee/Reproductive Health Matters, London, UK
                [2 ]GRID grid.208078.5, ISNI 0000000419370394, Department of Community Medicine, , University of Connecticut School of Medicine, ; Farmington, CT 06030-6325 USA
                [3 ]GRID grid.416651.1, ISNI 0000000091206856, Istituto Superiore di Sanità, ; Rome, Italy
                [4 ]Cochrane Editorial Unit, London, UK
                [5 ]GRID grid.475176.6, Journal of the International AIDS Society, ; Geneva, Switzerland
                Article
                7
                10.1186/s41073-016-0007-6
                5793986
                29451543
                639d838a-8dc3-4e70-a0e1-3e108451361d
                © The Author(s) 2016

                Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License ( http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

                History
                : 3 November 2015
                : 13 March 2016
                Categories
                Review
                Custom metadata
                © The Author(s) 2016

                sex,gender,guidelines,sager,scientific research,scientific publishing,gender bias,equity

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