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Fluorescent probes designed for detecting human serum albumin on the basis of its pseudo-esterase activity.

Author(s): Joo Park, Shi-Woo Rhee, Hyo Young Kim, Jee-Yeon Kim, Ki Kim, In-Sun Hong

Publication date: 2013-04-01

Journal: Bioorganic & Medicinal Chemistry Letters

Keywords: Cell Line, Tumor, Enzyme Activation, Esterases, metabolism, Flow Cytometry, Fluorescent Dyes, chemical synthesis, chemistry, Humans, Leukemia, Monocytic, Acute, pathology, Microscopy, Fluorescence, Models, Molecular, Molecular Structure, Serum Albumin, analysis

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Abstract

We developed activity-based fluorescent probes for detecting human serum albumin (HSA) on the basis of its pseudo-esterase activity. These probes could also detect HSA in blood-contaminated tissue samples. Copyright © 2013 Elsevier Ltd. All rights reserved.

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PubMed ID:: 23453074

DOI:: 10.1016/j.bmcl.2013.01.124

ScienceOpen disciplines: Chemistry

Keywords: Cell Line, Tumor,Enzyme Activation,Esterases,metabolism,Flow Cytometry,Fluorescent Dyes,chemical synthesis,chemistry,Humans,Leukemia, Monocytic, Acute,pathology,Microscopy, Fluorescence,Models, Molecular,Molecular Structure,Serum Albumin,analysis

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ScienceOpen disciplines: Chemistry

Fluorescent probes designed for detecting human serum albumin on the basis of its pseudo-esterase activity.

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