+1 Recommend
1 collections
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Exploring the relationship between mental health, drug use, personality, and attitudes towards psilocybin-assisted therapy


      Read this article at

          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.



          Psilocybin, the psychoactive compound in magic mushrooms, is increasingly discussed in terms of its psychotherapeutic potential; however, little is known about community attitudes towards psilocybin assisted therapy (PAT).


          To address the question: What are the public's attitudes towards psilocybin and psilocybin-assisted therapy? And what factors explain these attitudes?


          This study investigated the attitudes of 118 young adults in the Australian Capital Territory through an online survey.


          Participants who were more open to experience and who had used recreational drugs were more likely to have positive attitudes towards all aspects of PAT. Additionally, psychedelic drug use and agreeableness was positively associated with attitudes towards psilocybin safety, legality, and research; and psilocybin use was positively associated with attitudes towards psilocybin knowledge and acceptability.


          This convenience sample of young adults was generally positively disposed towards PAT. People who were more open to experience and who had used recreational or psychedelic drugs had more favourable attitudes towards PAT.

          Related collections

          Most cited references20

          • Record: found
          • Abstract: found
          • Article: not found

          Empirical, theoretical, and practical advantages of the HEXACO model of personality structure.

          The authors argue that a new six-dimensional framework for personality structure--the HEXACO model--constitutes a viable alternative to the well-known Big Five or five-factor model. The new model is consistent with the cross-culturally replicated finding of a common six-dimensional structure containing the factors Honesty-Humility (H), Emotionality (E), eExtraversion (X), Agreeableness (A), Conscientiousness (C), and Openness to Experience (O). Also, the HEXACO model predicts several personality phenomena that are not explained within the B5/FFM, including the relations of personality factors with theoretical biologists' constructs of reciprocal and kin altruism and the patterns of sex differences in personality traits. In addition, the HEXACO model accommodates several personality variables that are poorly assimilated within the B5/FFM.
            • Record: found
            • Abstract: not found
            • Article: not found

            The development of markers for the Big-Five factor structure.

              • Record: found
              • Abstract: found
              • Article: not found

              Mystical-type experiences occasioned by psilocybin mediate the attribution of personal meaning and spiritual significance 14 months later.

              Psilocybin has been used for centuries for religious purposes; however, little is known scientifically about its long-term effects. We previously reported the effects of a double-blind study evaluating the psychological effects of a high psilocybin dose. This report presents the 14-month follow-up and examines the relationship of the follow-up results to data obtained at screening and on drug session days. Participants were 36 hallucinogen-naïve adults reporting regular participation in religious/ spiritual activities. Oral psilocybin (30 mg/70 kg) was administered on one of two or three sessions, with methylphenidate (40 mg/70 kg) administered on the other session(s). During sessions, volunteers were encouraged to close their eyes and direct their attention inward. At the 14-month follow-up, 58% and 67%, respectively, of volunteers rated the psilocybin-occasioned experience as being among the five most personally meaningful and among the five most spiritually significant experiences of their lives; 64% indicated that the experience increased well-being or life satisfaction; 58% met criteria for having had a 'complete' mystical experience. Correlation and regression analyses indicated a central role of the mystical experience assessed on the session day in the high ratings of personal meaning and spiritual significance at follow-up. Of the measures of personality, affect, quality of life and spirituality assessed across the study, only a scale measuring mystical experience showed a difference from screening. When administered under supportive conditions, psilocybin occasioned experiences similar to spontaneously occurring mystical experiences that, at 14-month follow-up, were considered by volunteers to be among the most personally meaningful and spiritually significant of their lives.

                Author and article information

                Journal of Psychedelic Studies
                Akadémiai Kiadó (Budapest )
                21 August 2023
                [1] University of Canberra , Australia
                Author notes
                [* ]Corresponding author. E-mail: benjaminross068@ 123456gmail.com
                Author information
                © 2023 The Author(s)

                Open Access statement. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( https://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted use, distribution, and reproduction in any medium for non-commercial purposes, provided the original author and source are credited, a link to the CC License is provided, and changes – if any – are indicated.

                : 14 February 2023
                : 14 July 2023
                : 26 July 2023
                Page count
                Tables: 2, Equations: 0, References: 22, Pages: 05
                Funded by: University of Canberra

                Evolutionary Biology,Medicine,Psychology,Educational research & Statistics,Social & Behavioral Sciences
                psilocybin,attitudes,mental health,psilocybin-assisted therapy,personality


                Comment on this article