Sapotaceae is historically known as having a tricky and challenging taxonomy due to tangled morphologic heterogeneity. Consequently, this resulted in a large number of described genera and binomials. After Pennington’s Flora Neotropica work, several of those nomenclature issues were resolved. Nevertheless, many binomials remain unsolved and up for typification. Thus, following the International Code of Nomenclature for Algae , Fungi and Plants, we propose 74 new lectotype designations, four of these are second-step typifications.