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      Mannose-binding lectin gene polymorphism and risk factors for cardiovascular disease in postmenopausal women.

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          Abstract

          Inflammatory responses may be altered in postmenopausal women and predispose to cardiovascular disease (CVD). Genetic factors can also influence susceptibility to CVD. Mannose-binding lectin (MBL) is a component of the innate immune system and an activator of the complement cascade. We evaluated the association of genetic polymorphism of MBL (MBL2) on risk factors for CVD in postmenopausal women.

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          Author and article information

          Journal
          Mol. Immunol.
          Molecular immunology
          Elsevier BV
          1872-9142
          0161-5890
          Sep 2014
          : 61
          : 1
          Affiliations
          [1 ] Department of Gynecology and Obstetrics, Botucatu Medical School, Sao Paulo State University- UNESP, Botucatu, São Paulo, Brazil. Electronic address: claudiorsatti@gmail.com.
          [2 ] Department of Gynecology and Obstetrics, Botucatu Medical School, Sao Paulo State University- UNESP, Botucatu, São Paulo, Brazil.
          [3 ] Department of Sports Science, Institute of Health Sciences - UFTM, Uberaba, Minas Gerais, Brazil.
          [4 ] Department of Gynecology and Obstetrics, University of Sao Paulo Medical School, Sao Paulo, Brazil.
          [5 ] Department of Obstetrics and Gynecology, Division of Immunology and Infectious Diseases, Weill Cornell Medical College, New York, NY, USA.
          Article
          S0161-5890(14)00099-6
          10.1016/j.molimm.2014.05.003
          24861434
          647fc63c-a370-4bb6-9ca0-f8a9d09d97aa
          History

          Postmenopausal women,Polymorphism,Cardiovascular disease,Mannose-binding lectin

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