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Soft Tissue Sarcoma, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology
Margaret von Mehren ,
R. Lor Randall ,
Robert S. Benjamin ,
Sarah Boles ,
Marilyn M. Bui ,
Kristen N. Ganjoo ,
Suzanne George ,
Ricardo J. Gonzalez ,
Martin J. Heslin ,
John M. Kane ,
Vicki Keedy ,
Edward Kim ,
Henry Koon ,
Joel Mayerson ,
Martin McCarter ,
Sean V. McGarry ,
Christian Meyer ,
Zachary S. Morris ,
Richard J. O'Donnell ,
Alberto S. Pappo ,
I. Benjamin Paz ,
Ivy A. Petersen ,
John D. Pfeifer ,
Richard F. Riedel ,
Bernice Ruo ,
Scott Schuetze ,
William D. Tap ,
Jeffrey D. Wayne ,
Mary Anne Bergman ,
Jillian L. Scavone
May 11 2018
May 11 2018
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Abstract
Soft tissue sarcomas (STS) are rare solid tumors of mesenchymal cell origin that display
a heterogenous mix of clinical and pathologic characteristics. STS can develop from
fat, muscle, nerves, blood vessels, and other connective tissues. The evaluation and
treatment of patients with STS requires a multidisciplinary team with demonstrated
expertise in the management of these tumors. The complete NCCN Guidelines for STS
provide recommendations for the diagnosis, evaluation, and treatment of extremity/superficial
trunk/head and neck STS, as well as intra-abdominal/retroperitoneal STS, gastrointestinal
stromal tumors, desmoid tumors, and rhabdomyosarcoma. This portion of the NCCN Guidelines
discusses general principles for the diagnosis, staging, and treatment of STS of the
extremities, superficial trunk, or head and neck; outlines treatment recommendations
by disease stage; and reviews the evidence to support the guidelines recommendations.