32
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Experimental Infection and Natural Contact Exposure of Dogs with Avian Influenza Virus (H5N1)

      brief-report

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Experiments that exposed influenza virus (H5N1)–infected cats to susceptible dogs did not result in intraspecies or interspecies transmission. Infected dogs showed increased body temperatures, viral RNA in pharyngeal swabs, and seroconversion but not fatal disease.

          Related collections

          Most cited references11

          • Record: found
          • Abstract: found
          • Article: not found

          Transmission of equine influenza virus to dogs.

          Molecular and antigenic analyses of three influenza viruses isolated from outbreaks of severe respiratory disease in racing greyhounds revealed that they are closely related to H3N8 equine influenza virus. Phylogenetic analysis indicated that the canine influenza virus genomes form a monophyletic group, consistent with a single interspecies virus transfer. Molecular changes in the hemagglutinin suggested adaptive evolution in the new host. The etiologic role of this virus in respiratory disease was supported by the temporal association of rising antibody titers with disease and by experimental inoculation studies. The geographic expansion of the infection and its persistence for several years indicate efficient transmission of canine influenza virus among greyhounds. Evidence of infection in pet dogs suggests that this infection may also become enzootic in this population.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Avian H5N1 influenza in cats.

            During the 2003 to 2004 outbreak of avian influenza A (H5N1) virus in Asia, there were anecdotal reports of fatal infection in domestic cats, although this species is considered resistant to influenza. We experimentally inoculated cats with H5N1 virus intratracheally and by feeding them virus-infected chickens. The cats excreted virus, developed severe diffuse alveolar damage, and transmitted virus to sentinel cats. These results show that domestic cats are at risk of disease or death from H5N1 virus, can be infected by horizontal transmission, and may play a role in the epidemiology of this virus.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: found
              Is Open Access

              Avian Influenza H5N1 in Tigers and Leopards

              Influenza virus is not known to affect wild felids. We demonstrate that avian influenza A (H5N1) virus caused severe pneumonia in tigers and leopards that fed on infected poultry carcasses. This finding extends the host range of influenza virus and has implications for influenza virus epidemiology and wildlife conservation.
                Bookmark

                Author and article information

                Journal
                Emerg Infect Dis
                EID
                Emerging Infectious Diseases
                Centers for Disease Control and Prevention
                1080-6040
                1080-6059
                February 2008
                : 14
                : 2
                : 308-310
                Affiliations
                [* ]Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany
                Author notes
                Address for correspondence: Thomas W. Vahlenkamp, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, 17493 Greifswald-Insel Riems, Germany; email: thomas.vahlenkamp@ 123456fli.bund.de
                Article
                07-0864
                10.3201/eid1402.070864
                2600189
                18258127
                650290e2-ee0e-4687-a615-29749bbe96b0
                History
                Categories
                Dispatch

                Infectious disease & Microbiology
                dispatch,highly pathogenic avian influenza (h5n1) virus,feline,dog,susceptibility,canine,cat

                Comments

                Comment on this article