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      Impact of statins on progression of atherosclerosis: rationale and design of SATURN (Study of Coronary Atheroma by InTravascular Ultrasound: effect of Rosuvastatin versus AtorvastatiN).

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          Abstract

          Previous imaging studies have demonstrated that the beneficial impact of high-dose statins on the progression of coronary atherosclerosis associates with their ability to lower levels of low-density lipoprotein cholesterol (LDL-C) and C-reactive protein (CRP) and to raise high-density lipoprotein cholesterol (HDL-C). The Study of Coronary Atheroma by InTravascular Ultrasound: Effect of Rosuvastatin versus AtorvastatiN (SATURN, NCT00620542) aims to compare the effects of high-dose atorvastatin and rosuvastatin on disease progression.

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          Author and article information

          Journal
          Curr Med Res Opin
          Current medical research and opinion
          Informa Healthcare
          1473-4877
          0300-7995
          Jun 2011
          : 27
          : 6
          Affiliations
          [1 ] Department of Cardiovascular Medicine , Cleveland Clinic, Cleveland, OH , USA.
          Article
          10.1185/03007995.2011.570746
          21446892
          6503ca86-58c7-42a5-90fe-856a82aa3e0f
          History

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