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      Bioreactor Design and Scale-Up

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          Cell culture on artificial capillaries: an approach to tissue growth in vitro.

          Artificial capillaries perfused with culture medium provide a matrix in which cells can attain tissue-like densities in vitro. Products secreted into the medium can be measured as indicators of cell function or may be recovered for other purposes without disturbing the culture.
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            Animal-cell damage in sparged bioreactors.

            The gas sparging of culture broth causes damage to suspended animal cells. However, despite this, sparged bioreactors remain the preferred means of cell culture because sparging is a robust method of supplying oxygen, especially on a large scale. This article examines the underlying mechanisms involved in bubble-associated cell damage and the methods available for controlling such damage.
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              Animal Cell Culture and Technology

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                Book Chapter
                2009
                : 173-259
                10.1007/978-3-540-68182-3_5
                6512eb2d-8543-4d25-a398-87981f035d3b
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