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      Recent Advances in Garcinia cambogia Nutraceuticals in Relation to Its Hydroxy Citric Acid Level. A Comprehensive Review of Its Bioactive Production, Formulation, and Analysis with Future Perspectives

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      ACS Omega
      American Chemical Society

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          Abstract

          Garcinia cambogia (Gaertn.) Desr. (known as Malabar tamarind) is a popular traditional herbal medicine and is one of the well-known folk medicines reported for the treatment of obesity and incorporated in several nutraceuticals worldwide. These effects are mediated by a myriad of bioactive compounds with most effects attributed to its hydroxy citric acid (HCA) content. This review aims to present a holistic overview on novel trends in the production of G. cambogia bioactive components and how extraction optimization is important to ensure best product quality with its reported nanoformulations with particular emphasis on HCA content. Further, an overview of the different analytical approaches used for quality control assessment of G. cambogia plant and its nutraceuticals is presented highlighting both advantages and limitations. Moreover, analytical approaches for detecting G. cambogia metabolites in biological fluids with emphasis on HCA level to determine its pharmacokinetics and proof of efficacy are presented for the first time.

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          Solid lipid nanoparticles (SLN) for controlled drug delivery – a review of the state of the art

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            A review on green synthesis of silver nanoparticles and their applications.

            Development of reliable and eco-accommodating methods for the synthesis of nanoparticles is a vital step in the field of nanotechnology. Silver nanoparticles are important because of their exceptional chemical, physical, and biological properties, and hence applications. In the last decade, numerous efforts were made to develop green methods of synthesis to avoid the hazardous byproducts. This review describes the methods of green synthesis for Ag-NPs and their numerous applications. It also describes the comparison of efficient synthesis methods via green routes over physical and chemical methods, which provide strong evidence for the selection of suitable method for the synthesis of Ag-NPs.
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              α-Mangostin from Garcinia mangostana Linn: An updated review of its pharmacological properties

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                Author and article information

                Journal
                ACS Omega
                ACS Omega
                ao
                acsodf
                ACS Omega
                American Chemical Society
                2470-1343
                19 July 2022
                02 August 2022
                : 7
                : 30
                : 25948-25957
                Affiliations
                []Pharmacognosy Department, Faculty of Pharmacy, Egyptian Russian University , Badr City, Cairo 11829, Egypt
                []Pharmacognosy Department, Faculty of Pharmacy, Modern University for Technology & Information , Cairo 11835, Egypt
                [§ ]Pharmacognosy Department, College of Pharmacy, Cairo University , Kasr El-Aini St., Cairo 11562, Egypt
                Author notes
                [* ]Email: mohamed.farag@ 123456pharma.cu.edu.eg . Tel: +011-202-2362245. Fax: +011-202-25320005.
                Author information
                https://orcid.org/0000-0002-8597-7974
                https://orcid.org/0000-0001-5139-1863
                Article
                10.1021/acsomega.2c02838
                9352243
                35936438
                6546069d-12c5-44dd-b267-d7db63b20fc3
                © 2022 The Authors. Published by American Chemical Society

                Permits non-commercial access and re-use, provided that author attribution and integrity are maintained; but does not permit creation of adaptations or other derivative works ( https://creativecommons.org/licenses/by-nc-nd/4.0/).

                History
                : 07 May 2022
                : 07 July 2022
                Categories
                Review
                Custom metadata
                ao2c02838
                ao2c02838

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