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      Recomendaciones para la práctica clínica sobre el manejo de la actividad física, ejercicio y deporte en niños, niñas y adolescentes con diabetes mellitus tipo 1

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          Abstract

          Resumen La presente recomendación busca brindar un marco de seguridad para la prescripción de actividad física en niños, niñas y adolescentes con diabetes mellitus tipo 1 (DM1), considerando la evaluación de las situaciones que puedan presentarse antes, durante y después de su práctica. Incluye las estrategias terapéuticas sobre el tipo de ejercicio, el control glucémico capilar(o mediante el uso de monitoreo continuo de glucosa, MCG) y la adecuación de la insulinoterapia y de la ingesta de hidratos de carbono. Se prioriza que, para optimizar los beneficios del ejercicio como parte del tratamiento de la DM1, es importante una complete y constant educación diabetológica para el paciente y sus cuidadores brindada por un equipo interdisciplinario entrenado en el manejo integral de niños, niñas y adolescentescon DM1.

          Translated abstract

          Abstract These recommendations seek to provide a safety framework for the prescription of physical activity in children and adolescents with DM1, considering the evaluation of the situations that may arise before, during and after the practice of physical activity. It includes therapeutic strategies on the type of exercise, intensive capillary glycemic control or through the use of continuous glucose monitoring (CGM) and the adequacy of insulin therapy and carbohydrate intake. It is prioritized that to optimize the benefits of exercise as part of the treatment of DM1, a complete and constant diabetes education is important, provided by an interdisciplinary team trained in the comprehensive management of children and adolescents with DM1.

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          ISPAD Clinical Practice Consensus Guidelines 2018: Exercise in children and adolescents with diabetes

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            Exercise reduces circulating biomarkers of cellular senescence in humans

            Cellular senescence has emerged as a significant and potentially tractable mechanism of aging and multiple aging‐related conditions. Biomarkers of senescent cell burden, including molecular signals in circulating immune cells and the abundance of circulating senescence‐related proteins, have been associated with chronological age and clinical parameters of biological age in humans. The extent to which senescence biomarkers are affected by interventions that enhance health and function has not yet been examined. Here, we report that a 12‐week structured exercise program drives significant improvements in several performance‐based and self‐reported measures of physical function in older adults. Impressively, the expression of key markers of the senescence program, including p16, p21, cGAS , and TNFα , were significantly lowered in CD3 + T cells in response to the intervention, as were the circulating concentrations of multiple senescence‐related proteins. Moreover, partial least squares discriminant analysis showed levels of senescence‐related proteins at baseline were predictive of changes in physical function in response to the exercise intervention. Our study provides first‐in‐human evidence that biomarkers of senescent cell burden are significantly lowered by a structured exercise program and predictive of the adaptive response to exercise. Our study provides first‐in‐human evidence that biomarkers of senescent cell burden are significantly lowered by a structured exercise program and predictive of the adaptive response to exercise.
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              Insulin Management Strategies for Exercise in Diabetes

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                Author and article information

                Journal
                rsad
                Revista de la Sociedad Argentina de Diabetes
                Rev. Soc. Argent. Diabetes
                Sociedad Argentina de Diabetes (CABA, , Argentina )
                0325-5247
                2346-9420
                May 2022
                : 56
                : suppl 1
                : 29-35
                Affiliations
                [3] orgnameHospital de Niños La Santísima Trinidad, Córdoba Argentina
                [1] orgnameHospital Regional Neuquén, Neuquén Argentina
                [4] orgnameHospital Churruca Visca, Ciudad Autónoma de Buenos Aires Argentina
                [2] orgnameFundación Hospitalaria, Sociedad Argentina de Diabetes (SAD), Ciudad Autónoma de Buenos Aires Argentina
                [5] orgnameHospital Nacional Posadas, Hospital Italiano de Buenos Aires, Ciudad Autónoma de Buenos Aires Argentina
                Article
                S2346-94202022000300029 S2346-9420(22)05600000029
                65466c58-9dca-4117-9dc5-5e1cdb8f2d7e

                This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

                History
                : 22 June 2022
                : 09 March 2022
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 8, Pages: 7
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                SciELO Argentina

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                ejercicio,insulin,self-monitoring,type 1 diabetes mellitus,exercise,carbohidratos,insulina,automonitoreo,diabetes mellitus tipo 1,carbohydrates

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