Annexin-2 is a regulator of stromal cell-derived factor-1/CXCL12 function in the hematopoietic stem cell endosteal niche.

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Abstract

Previously, we reported that annexin-2 (anxa2) plays an important role in hematopoietic stem cell (HSC) localization to the endosteal/osteoblastic marrow niche. This study explored the role that annexin-2 plays in presenting stromal cell-derived factor-1 (or CXCL12) to HSCs.

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Journal

Journal ID (iso-abbrev): Exp. Hematol.

Title: Experimental hematology

ISSN (Electronic): 1873-2399

ISSN (Print): 0301-472X

Publication date (Electronic): Feb 2011

Volume: 39

Issue: 2

Affiliations

[1 ] Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, 1011 North University Avenue, Ann Arbor, MI 48109-1078, USA.

Article

Publisher Item ID: S0301-472X(10)00554-0 Mid ID: NIHMS258860

DOI: 10.1016/j.exphem.2010.11.007

PMC ID: 3026087

PubMed ID: 21108988

SO-VID: 65658fbb-4f17-4d59-bbfa-c4274618173a

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