Sulfonylurea use is associated with larger infarct size in patients with diabetes and ST-elevation myocardial infarction.

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Abstract

Animal models have demonstrated that sulfonylureas increase the size of myocardial infarction; however, data in humans is scarce. This study evaluated the association between sulfonylurea use and infarct size in diabetes patients with ST-elevation myocardial infarction (STEMI).

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Journal

Journal ID (iso-abbrev): Int. J. Cardiol.

Title: International journal of cardiology

Publisher: Elsevier BV

ISSN (Electronic): 1874-1754

ISSN (Print): 0167-5273

Publication date (Electronic): Jan 01 2016

Volume: 202

Affiliations

[1 ] Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada.; Alliance for Canadian Health Outcomes Research in Diabetes, University of Alberta, Edmonton, AB, Canada.

[2 ] Division of Cardiology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.

[3 ] Alliance for Canadian Health Outcomes Research in Diabetes, University of Alberta, Edmonton, AB, Canada; Department of Public Health Sciences, School of Public Health, University of Alberta, Edmonton, AB, Canada.

[4 ] Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada.; Alliance for Canadian Health Outcomes Research in Diabetes, University of Alberta, Edmonton, AB, Canada. Electronic address: scot@ualberta.ca.

Article

Publisher Item ID: S0167-5273(15)30441-1

DOI: 10.1016/j.ijcard.2015.08.213

PubMed ID: 26386939

SO-VID: 657ecbfd-eaf2-4fb5-a57e-83c07937b03e

History

Keywords: Type 2 diabetes,ST-elevation myocardial infarction,Infarct size,Sulfonylureas

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Keywords: Type 2 diabetes, ST-elevation myocardial infarction, Infarct size, Sulfonylureas

Sulfonylurea use is associated with larger infarct size in patients with diabetes and ST-elevation myocardial infarction.

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