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      Naevus of the Optic Nerve

      Ophthalmic Research
      S. Karger AG
      Naevus, Melanocytes, Optic atrophy, Loss of ganglion cells, Optic nerve

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          A single autopsy case is reported of a fair-skinned, hazel-eyed Caucasian female who had had visual complaints and who, at autopsy, was found to have two separate melanocytic lesions involving the retrolaminar portion of the optic nerve and the superior wall of the scleral canal. The optic nerve lesion had not been seen ophthal-moscopically and a routine, post mortem gross examination of the eye did not reveal pigmentation of the nerve head. The pigmented lesions consisted of loosely-arrayed, fusiform, branching, and dendritic melanocytes. These lesions had the cytological appearances of a blue naevus. Naevi of the optic nerve form a spectrum, somewhat analogous to that recognized in the uveal tract.

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          Author and article information

          Ophthalmic Res
          Ophthalmic Research
          S. Karger AG
          03 December 2009
          : 8
          : 4
          : 276-282
          Eye Pathology Laboratory, Wilmer Institute and Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, Md
          264833 Ophthalmic Res 1976;8:276–282
          © 1976 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          : 10 September 1975
          : 30 March 1976
          Page count
          Pages: 7

          Vision sciences,Ophthalmology & Optometry,Pathology
          Melanocytes,Optic atrophy,Loss of ganglion cells,Naevus,Optic nerve


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