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      Possible roles of Runx1 and Sox9 in incipient intramembranous ossification.

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          Abstract

          We evaluated the detailed expression patterns of Runx1 and Sox9 in various types of bone formation, and determined whether Runx1 expression was affected by Runx2 deficiency and Runx2 expression by Runx1 deficiency. Our results indicate that both Runx1 and Sox9 are intensely expressed in the future osteogenic cell compartment and in cartilage. The pattern of Runx1 and Sox9 expression suggests that both genes could potentially be involved in incipient intramembranous bone formation during craniofacial development.

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          Author and article information

          Journal
          J. Bone Miner. Res.
          Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
          Wiley
          0884-0431
          0884-0431
          Oct 2004
          : 19
          : 10
          Affiliations
          [1 ] Department of Orthodontics, Graduate School of Medicine and Dentistry, Okayama University, Okayama, Japan. yamat@md.okayama-u.ac.jp
          Article
          10.1359/JBMR.040801
          15355562
          65cdab33-8fdb-4748-8476-d0c586b0ca51
          History

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