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      A multienergy computed tomography method without image segmentation or prior knowledge of X-ray spectra or materials

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          Abstract

          Many methods have been proposed for multienergy computed tomography (CT) imaging based on traditional CT systems. Usually, either prior knowledge of the X-ray spectra distribution or materials or the segmentation of the projection or reconstructed image is needed. To avoid these requirements, a multienergy CT method is proposed in this paper. A CT image can be seen as a linear combination of energy-dependent components and spatially dependent components. The latter components are the base images, while the former components are the coefficients. A blind decomposition model is constructed to decompose the multivoltage projections to obtain the base images and the energies. Multienergy CT images are computationally synthesized with the base images and the energies. Multivoltage projections can be acquired based on one scan with stepped voltages. X-ray scattering is considered an important factor in imaging errors and appears as a low-frequency signal. The variance is used to describe the low-frequency features and is minimized as the optimized objective function of the decomposition model. The solution of the model uses Karush–Kuhn–Tucker (KKT) conditions. In the experiments, the images reconstructed with the proposed method exhibit weak beam-hardening artifacts. Additionally, the X-ray energies of the different materials represented have small relative errors. Therefore, the reconstructed images have narrow energy intervals. This shows the effectiveness of the proposed method.

          Abstract

          Computed tomography; Multienergy; Multivoltage projections; Blind decomposition; One scan; Prior knowledge

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          Most cited references49

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          Deep learning-based meta-classifier approach for COVID-19 classification using CT scan and chest X-ray images

          Literature survey shows that convolutional neural network (CNN)-based pretrained models have been largely used for CoronaVirus Disease 2019 (COVID-19) classification using chest X-ray (CXR) and computed tomography (CT) datasets. However, most of the methods have used a smaller number of data samples for both CT and CXR datasets for training, validation, and testing. As a result, the model might have shown good performance during testing, but this type of model will not be more effective on unseen COVID-19 data samples. Generalization is an important term to be considered while designing a classifier that can perform well on completely unseen datasets. Here, this work proposes a large-scale learning with stacked ensemble meta-classifier and deep learning-based feature fusion approach for COVID-19 classification. The features from the penultimate layer (global average pooling) of EfficientNet-based pretrained models were extracted and the dimensionality of the extracted features reduced using kernel principal component analysis (PCA). Next, a feature fusion approach was employed to merge the features of various extracted features. Finally, a stacked ensemble meta-classifier-based approach was used for classification. It is a two-stage approach. In the first stage, random forest and support vector machine (SVM) were applied for prediction, then aggregated and fed into the second stage. The second stage includes logistic regression classifier that classifies the data sample of CT and CXR into either COVID-19 or Non-COVID-19. The proposed model was tested using large CT and CXR datasets, which are publicly available. The performance of the proposed model was compared with various existing CNN-based pretrained models. The proposed model outperformed the existing methods and can be used as a tool for point-of-care diagnosis by healthcare professionals.
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            Dual-Energy Computed Tomography

            There are increasing applications of dual-energy computed tomography (CT), a type of spectral CT, in neuroradiology and head and neck imaging. In this 2-part review, the fundamental principles underlying spectral CT scanning and the major considerations in implementing this type of scanning in clinical practice are reviewed. In the first part of this 2-part review, the physical principles underlying spectral CT scanning are reviewed, followed by an overview of the different approaches for spectral CT scanning, including a discussion of the strengths and challenges encountered with each approach.
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              Joint Statistical Iterative Material Image Reconstruction for Spectral Computed Tomography Using a Semi-Empirical Forward Model

              By acquiring tomographic measurements with several distinct photon energy spectra, spectral computed tomography (spectral CT) is able to provide additional material-specific information compared with conventional CT. This information enables the generation of material selective images, which have found various applications in medical imaging. However, material decomposition typically leads to noise amplification and a degradation of the signal-to-noise ratio. This is still a fundamental problem of spectral CT, especially for low-dose medical applications. Inspired by the success for low-dose conventional CT, several statistical iterative reconstruction algorithms for spectral CT have been developed. These algorithms typically rely on detailed knowledge about the spectrum and the detector response. Obtaining this knowledge is often difficult in practice, especially if photon counting detectors are used to acquire the energy specific information. In this paper, a new algorithm for joint statistical iterative material image reconstruction is presented. It relies on a semi-empirical forward model which is tuned by calibration measurements. This strategy allows to model spatially varying properties of the imaging system without requiring detailed prior knowledge of the system parameters. We employ an efficient optimization algorithm based on separable surrogate functions to accelerate convergence and reduce the reconstruction time. Numerical as well as real experiments show that our new algorithm leads to reduced statistical bias and improved image quality compared with projection-based material decomposition followed by analytical or iterative image reconstruction.
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                Author and article information

                Contributors
                Journal
                Heliyon
                Heliyon
                Heliyon
                Elsevier
                2405-8440
                15 November 2022
                November 2022
                15 November 2022
                : 8
                : 11
                : e11584
                Affiliations
                [0010]Shanxi Key Laboratory of Signal Capturing & Processing, North University of China, Taiyuan 030051, People's Republic of China
                Author notes
                [* ]Corresponding author. pc0912@ 123456163.com
                Article
                S2405-8440(22)02872-9 e11584
                10.1016/j.heliyon.2022.e11584
                9674550
                36411882
                664122fb-33c6-48fa-97b9-c2b0485085c7
                © 2022 The Authors. Published by Elsevier Ltd.

                This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

                History
                : 10 February 2022
                : 1 May 2022
                : 7 November 2022
                Categories
                Research Article

                computed tomography,multienergy,multivoltage projections,blind decomposition,one scan,prior knowledge

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