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      Choice of Sclerosant: An Experimental Study

      research-article
      Journal of Vascular Research
      S. Karger AG
      Experimental study, Sclerosants, Hydroxy-polyethoxydodecan, Tetradecylsulphate

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          Abstract

          The sclerosant hydroxypolyethoxydodecan (HPD) was studied in rats, and the results were compared with those from a previous study of tetradecyl sulphate of sodium (TSS). There appeared to be no significant difference between the two. The sclerosant efficiency increased with increasing concentration up to 6%, but a higher concentration than 6% is unlikely to be more effective in the rat or in man. In man, good results probably depend on exposure of the endothelium to sclerosant undiluted with blood for 1 s, and the total volume of 6% HPD or 6% TSS injected at one visit should not exceed 10 ml.

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          Author and article information

          Journal
          JVR
          J Vasc Res
          10.1159/issn.1018-1172
          Journal of Vascular Research
          S. Karger AG
          1018-1172
          1423-0135
          1970
          1970
          18 September 2008
          : 7
          : 3
          : 182-186
          Affiliations
          Department of Pathology, St. Mary’s Hospital Medical School, London
          Article
          157833 Angiologica 1970;7:182–186
          10.1159/000157833
          6641eaa1-7df2-4404-a64b-960caaba6301
          © 1970 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          Page count
          Pages: 5
          Categories
          Paper

          General medicine,Neurology,Cardiovascular Medicine,Internal medicine,Nephrology
          Hydroxy-polyethoxydodecan,Tetradecylsulphate,Experimental study,Sclerosants

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