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      Renal Tubular Dysfunction in a Patient with Beta-Thalassemia Minor

      ,

      Nephron

      S. Karger AG

      Glucosuria, Tubular proteinuria, Beta-thalassemia minor

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          Abstract

          β-Thalassemia minor is a hemoglobinopathy which has been known as a symptomless carrier state. Although there are many causes leading to renal tubular dysfunction, β-thalassemia minor has not been reported among them in reviewing the literature. In a 20-year-old male patient referred to us because of glucosuria detected with dipstick, there was also anemia (hemoglobin, 11.5 g/dl; mean cell volume, 60 fl; and mean cell hemoglobin concentration, 19.5 pg). The 24-hour urinary glucose excretion rate was 5 g and, additionally, he had tubular proteinuria (albumin/β<sub>2</sub>-microglobulin ratio in urine was 17.32). Based upon the detailed evaluation for both asymptomatic urinary abnormality and anemia, he was diagnosed as having renal tubular dysfunction and β-thalassemia minor (hemoglobin A<sub>1 </sub>was 91%, and hemoglobin A<sub>2 </sub>was 9%). In conclusion, further reports are needed to reveal whether there is an association between these two distinct disorders.

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          Author and article information

          Journal
          NEF
          Nephron
          10.1159/issn.1660-8151
          Nephron
          S. Karger AG
          1660-8151
          2235-3186
          2002
          September 2002
          14 August 2002
          : 92
          : 1
          : 222-223
          Affiliations
          Department of Internal Medicine, Gülhane Military Medical Academy and Faculty, Etlik, Ankara, Turkey
          Article
          64463 Nephron 2002;92:222–223
          10.1159/000064463
          12187108
          © 2002 S. Karger AG, Basel

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          Page count
          References: 5, Pages: 2
          Product
          Self URI (application/pdf): https://www.karger.com/Article/Pdf/64463
          Categories
          Short Communication

          Cardiovascular Medicine, Nephrology

          Beta-thalassemia minor, Tubular proteinuria, Glucosuria

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