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Dextran sodium sulfate-induced colitis causes rapid bone loss in mice.
Gilad Hamdani
1 ,
Yankel Gabet ,
Daniel Rachmilewitz ,
Fanny Karmeli ,
Itai Bab ,
Rivka Dresner-Pollak
Nov 2008
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Abstract
Osteopenia is a common complication of human inflammatory bowel disease (IBD). We evaluated the contribution of colonic inflammation to osteopenia and its mechanism in a murine colitis model.