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      Fenofibrate improves high-fat diet-induced and palmitate-induced endoplasmic reticulum stress and inflammation in skeletal muscle

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      Life Sciences

      Elsevier BV

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          Abstract

          Fenofibrate (FF) is commonly used clinically as a lipid-lowering drug, but whether it participates in endoplasmic reticulum (ER) stress and decreases inflammation in skeletal muscle is still unknown. The aim of this study is to determine whether FF treatment reduces insulin resistance (IR) by alleviating ER stress and downstream inflammation in skeletal muscle tissues and cells.

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          Author and article information

          Journal
          Life Sciences
          Life Sciences
          Elsevier BV
          00243205
          July 2016
          July 2016
          : 157
          : 158-167
          Article
          10.1016/j.lfs.2016.06.008
          27297630
          © 2016

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