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      Integrated RNA-sequencing and network pharmacology approach reveals the protection of Yiqi Huoxue formula against idiopathic pulmonary fibrosis by interfering with core transcription factors.

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          Abstract

          Idiopathic pulmonary fibrosis (IPF) is a refractory disease. Therefore, developing effective therapies for IPF is the need of the hour.

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          Author and article information

          Journal
          Phytomedicine
          Phytomedicine : international journal of phytotherapy and phytopharmacology
          Elsevier BV
          1618-095X
          0944-7113
          Sep 2022
          : 104
          Affiliations
          [1 ] Department of Respiratory Medicine, Central lab, Shenzhen Bao'an District Traditional Chinese Medicine Hospital, Yu'an Second Road, No. 21, Shenzhen 518133, China. Electronic address: lihang@gzucm.edu.cn.
          [2 ] Department of Respiratory Medicine, Central lab, Shenzhen Bao'an District Traditional Chinese Medicine Hospital, Yu'an Second Road, No. 21, Shenzhen 518133, China.
          [3 ] Guangzhou Chromap Biotechnology Co., Ltd., Guangzhou 510700, China.
          [4 ] Department of Respiratory Medicine, Central lab, Shenzhen Bao'an District Traditional Chinese Medicine Hospital, Yu'an Second Road, No. 21, Shenzhen 518133, China. Electronic address: zhoujihong71@gzucm.edu.cn.
          [5 ] The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China; Lingnan Medical Research Center of Guangzhou University of Chinese Medicine, Jichang Road, No. 12, Guangzhou 510405, China. Electronic address: huangxf28@foxmail.com.
          Article
          S0944-7113(22)00380-4
          10.1016/j.phymed.2022.154301
          35792448
          66f744ee-c544-4f39-9d7a-87ac24b1dcd3
          History

          Idiopathic pulmonary fibrosis,RNA-sequencing,Transcription factor,Yiqi Huoxue formula,Network pharmacology

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