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      Algorithms for Computing the Triplet Quartet Distances for Binary General Trees

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          Abstract

          Distance measures between trees are useful for comparing trees in a systematic manner, and several different distance measures have been proposed. The triplet and quartet distances, for rooted and unrooted trees, respectively, are defined as the number of subsets of three or four leaves, respectively, where the topologies of the induced subtrees differ. These distances can trivially be computed by explicitly enumerating all sets of three or four leaves and testing if the topologies are different, but this leads to time complexities at least of the order n 3 or n 4 just for enumerating the sets. The different topologies can be counted implicitly, however, and in this paper, we review a series of algorithmic improvements that have been used during the last decade to develop more efficient algorithms by exploiting two different strategies for this; one based on dynamic programming and another based on coloring leaves in one tree and updating a hierarchical decomposition of the other.

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          Comparison of phylogenetic trees

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            Matrix multiplication via arithmetic progressions

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              Comparison of Undirected Phylogenetic Trees Based on Subtrees of Four Evolutionary Units

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                Author and article information

                Journal
                Biology (Basel)
                Biology (Basel)
                biology
                Biology
                MDPI
                2079-7737
                26 September 2013
                December 2013
                : 2
                : 4
                : 1189-1209
                Affiliations
                [1 ]Department of Computer Science, Aarhus University, IT-Parken, Aabogade 34, DK-8200 Aarhus N, Denmark; E-Mails: asand@ 123456birc.au.dk (A.S.); the.thawk@ 123456gmail.com (M.K.H.); jens.joha@ 123456gmail.com (J.J.); gerth@ 123456cs.au.dk (G.S.B.); cstorm@ 123456birc.au.dk (C.N.S.P.)
                [2 ]Bioinformatics Research Centre, Aarhus University, C.F. Møllers Allé 8, DK-8000 Aarhus C, Denmark
                [3 ]Department of Mathematics and Computer Science, University of Southern Denmark, Campusvej 55, DK-5230 Odense M, Denmark; E-Mail: rolf@ 123456imada.sdu.dk
                [4 ]MADALGO -Center for Massive Data Algorithms, a Centre of the Danish National Research Foundation, Aabogade 34, DK-8200 Aarhus N, Denmark
                Author notes
                [* ]Author to whom correspondence should be addressed; E-Mail: mailund@ 123456birc.au.dk ; Tel.: +45-871-55562; Fax: +45-871-54102.
                Article
                biology-02-01189
                10.3390/biology2041189
                4009797
                24833220
                67018135-164f-4a5f-86b1-89d8481f7085
                © 2013 by the authors; licensee MDPI, Basel, Switzerland.

                This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license ( http://creativecommons.org/licenses/by/3.0/).

                History
                : 15 July 2013
                : 29 August 2013
                : 13 September 2013
                Categories
                Review

                algorithmic development,tree comparison,triplet distance,quartet distance

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