Left Ventricular Mass Index in End-Stage Renal Disease Patients during Hemodialysis and Continuous Ambulatory Peritoneal Dialysis

Abstract

Background

One of the primary reasons for high mortality in end-stage renal disease (ESRD) is cardiovascular disease in patients with renal replacement therapy (RRT). Left ventricular hypertrophy (LVH) significantly predicts mortality and cardiovascular events.

Objectives

We assess the left ventricular mass index change in two dialysis methods: hemodialysis (HD) and continuous ambulatory peritoneal dialysis (CAPD). The factors associated with increased left ventricular mass index (LVMI).

Materials and Methods

We recruit more than 50 HD patients and 45 CAPD patients with LVH of similar age, gender, dialysis duration, and LVMI for one-year follow-up.

Results

The LVMI in the group of HD patients after one year increased from 180.28 ± 45.32 g/m ² to 212.58 ± 66.22 g/m ² ( p = 0.001), while the LVMI in the group of patients with CAPD increased from 190.16 ± 66.01 g/m ² to 197.42 ± 78 g/m ² ( p = 0.32). Multivariable logistic regression analysis, we demonstrated that dialysis by HD ( β = −1,167, 95% CI: 0.104–0.938, p = 0.036) and anemia treatment lower the goals ( β = 1.9566, 95% CI: 1.466–34.094, p = 0.015) were two factors associated with the progression of the LVMI.

Conclusion

The LVH of end-stage renal disease patients with HD treatment is worse than CAPD treatment after a follow-up in one year. Dialysis by periodic hemodialysis and anemia treatment that fails to achieve the goal are risk factors associated with increased progression of LVMI in patients with ESRD.