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      Naftopidil for the treatment of lower urinary tract symptoms compatible with benign prostatic hyperplasia.

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          Abstract

          Benign prostatic hyperplasia (BPH) is a common condition in aging men causing lower urinary tract symptoms (LUTS). Treatment aims are to relieve symptoms and prevent disease progression. Of the different alpha-1 adrenergic receptors (ARs) in the prostate, alpha-1a receptors are known to be central to prostatic smooth-muscle contraction. Recent studies have shown that patients with BPH may also have a predominance of alpha-1d receptors.

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          Author and article information

          Journal
          Cochrane Database Syst Rev
          The Cochrane database of systematic reviews
          Wiley-Blackwell
          1469-493X
          1361-6137
          Oct 07 2009
          : 4
          Affiliations
          [1 ] John H. Stroger Hospital of Cook County, Chicago, Illinois, USA, 60607.
          10.1002/14651858.CD007360.pub2
          19821408

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