Odunayo O. Mugisho: Role: ConceptualizationRole: Formal analysisRole: InvestigationRole: MethodologyRole:
ValidationRole: VisualizationRole: Writing – original draftRole: Writing – review
& editing
Ilva D. Rupenthal:
ORCID: http://orcid.org/0000-0001-5997-5994
Role: ConceptualizationRole: Funding acquisitionRole: InvestigationRole: MethodologyRole:
Project administrationRole: ResourcesRole: SupervisionRole: VisualizationRole: Writing
– review & editing
David M. Squirrell: Role: Data curationRole: Formal analysisRole: InvestigationRole: ResourcesRole: ValidationRole:
VisualizationRole: Writing – review & editing
Sarah J. Bould: Role: Formal analysisRole: InvestigationRole: MethodologyRole: Project administrationRole:
ResourcesRole: ValidationRole: Writing – original draft
Helen V. Danesh-Meyer: Role: Formal analysisRole: ResourcesRole: ValidationRole: Writing – review & editing
Jie Zhang: Role: ConceptualizationRole: Formal analysisRole: MethodologyRole: ResourcesRole:
SupervisionRole: Writing – review & editing
Colin R. Green: Role: ConceptualizationRole: Formal analysisRole: Project administrationRole: SupervisionRole:
ValidationRole: VisualizationRole: Writing – review & editing
Monica L. Acosta:
ORCID: http://orcid.org/0000-0002-5018-339X
Role: ConceptualizationRole: Formal analysisRole: MethodologyRole: Project administrationRole:
ResourcesRole: SupervisionRole: ValidationRole: VisualizationRole: Writing – review
& editing
Alfred S Lewin: Role: Editor
Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
22
August
2018
Publication date Collection: 2018
Volume: 13
Issue: 8
Electronic Location Identifier: e0202156
Affiliations
[1
]
Buchanan Ocular Therapeutics Unit, Department of Ophthalmology and the New Zealand
National Eye Centre, University of Auckland, Auckland, New Zealand
[2
]
Department of Ophthalmology and the New Zealand National Eye Centre, University of
Auckland, Auckland, New Zealand
[3
]
School of Optometry and Vision Science and the New Zealand National Eye Centre, University
of Auckland, Auckland, New Zealand
University of Florida, UNITED STATES
Author notes
Competing Interests: We, the authors declare that no competing interests exist.
Author information
Article
Publisher ID:
PONE-D-18-16252
DOI: 10.1371/journal.pone.0202156
PMC ID: 6105000
PubMed ID: 30133488
SO-VID: 67f5fd98-b764-44fc-8429-a66801c3bec1
Copyright © © 2018 Mugisho et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
Funded by: funder-id http://dx.doi.org/10.13039/501100009477, Lottery Health Research;
The work was supported by 3707605 Lottery Health Research,
https://www.communitymatters.govt.nz/lottery-health-research/. The funders had no role in study design, data collection and analysis, decision
to publish, or preparation of the manuscript.
Subject:
Research Article
Subject:
Biology and Life Sciences
Subject:
Physiology
Subject:
Immune Physiology
Subject:
Cytokines
Subject:
Medicine and Health Sciences
Subject:
Physiology
Subject:
Immune Physiology
Subject:
Cytokines
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Immune System
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Innate Immune System
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Cytokines
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Medicine and Health Sciences
Subject:
Immunology
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Immune System
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Innate Immune System
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Cytokines
Subject:
Biology and Life Sciences
Subject:
Developmental Biology
Subject:
Molecular Development
Subject:
Cytokines
Subject:
Research and Analysis Methods
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Experimental Organism Systems
Subject:
Model Organisms
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Mouse Models
Subject:
Research and Analysis Methods
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Model Organisms
Subject:
Mouse Models
Subject:
Research and Analysis Methods
Subject:
Experimental Organism Systems
Subject:
Animal Models
Subject:
Mouse Models
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Head
Subject:
Eyes
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Head
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Eyes
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Biology and Life Sciences
Subject:
Anatomy
Subject:
Ocular System
Subject:
Eyes
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Medicine and Health Sciences
Subject:
Anatomy
Subject:
Ocular System
Subject:
Eyes
Subject:
Medicine and Health Sciences
Subject:
Endocrinology
Subject:
Endocrine Disorders
Subject:
Diabetes Mellitus
Subject:
Medicine and Health Sciences
Subject:
Metabolic Disorders
Subject:
Diabetes Mellitus
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Ocular System
Subject:
Ocular Anatomy
Subject:
Retina
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Ocular System
Subject:
Ocular Anatomy
Subject:
Retina
Subject:
Medicine and Health Sciences
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Inflammatory Diseases
Subject:
Biology and Life Sciences
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Anatomy
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Ocular System
Subject:
Optic Nerve
Subject:
Medicine and Health Sciences
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Anatomy
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Ocular System
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Optic Nerve
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Biology and Life Sciences
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Anatomy
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Body Fluids
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Blood
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Blood Sugar
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Body Fluids
Subject:
Blood
Subject:
Blood Sugar
Subject:
Biology and Life Sciences
Subject:
Physiology
Subject:
Body Fluids
Subject:
Blood
Subject:
Blood Sugar
Subject:
Medicine and Health Sciences
Subject:
Physiology
Subject:
Body Fluids
Subject:
Blood
Subject:
Blood Sugar
