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      Cardiac excitation-contraction coupling.

        1
      Nature
      Springer Science and Business Media LLC

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          Abstract

          Of the ions involved in the intricate workings of the heart, calcium is considered perhaps the most important. It is crucial to the very process that enables the chambers of the heart to contract and relax, a process called excitation-contraction coupling. It is important to understand in quantitative detail exactly how calcium is moved around the various organelles of the myocyte in order to bring about excitation-contraction coupling if we are to understand the basic physiology of heart function. Furthermore, spatial microdomains within the cell are important in localizing the molecular players that orchestrate cardiac function.

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          Author and article information

          Journal
          Nature
          Nature
          Springer Science and Business Media LLC
          0028-0836
          0028-0836
          Jan 10 2002
          : 415
          : 6868
          Affiliations
          [1 ] Department of Physiology, Stritch School of Medicine, Loyola Unversity Chicago, IL 60153, USA. dbers@lumc.edu
          Article
          415198a
          10.1038/415198a
          11805843
          6868cb3f-7798-4ed8-b9d8-f72ef90e54bb
          History

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