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      Searching for a baseline: Functional imaging and the resting human brain

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      Nature Reviews Neuroscience
      Springer Science and Business Media LLC

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          Abstract

          Functional brain imaging in humans has revealed task-specific increases in brain activity that are associated with various mental activities. In the same studies, mysterious, task-independent decreases have also frequently been encountered, especially when the tasks of interest have been compared with a passive state, such as simple fixation or eyes closed. These decreases have raised the possibility that there might be a baseline or resting state of brain function involving a specific set of mental operations. We explore this possibility, including the manner in which we might define a baseline and the implications of such a baseline for our understanding of brain function.

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          Author and article information

          Journal
          Nature Reviews Neuroscience
          Nat Rev Neurosci
          Springer Science and Business Media LLC
          1471-003X
          1471-0048
          October 2001
          October 2001
          : 2
          : 10
          : 685-694
          Article
          10.1038/35094500
          11584306
          68a429e7-d8e7-43fc-b161-b5565a1b3d00
          © 2001

          http://www.springer.com/tdm

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