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      Probiotics as Antiviral Agents in Shrimp Aquaculture

      review-article
      , , *
      Journal of Pathogens
      Hindawi Publishing Corporation

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          Abstract

          Shrimp farming is an aquaculture business for the cultivation of marine shrimps or prawns for human consumption and is now considered as a major economic and food production sector as it is an increasingly important source of protein available for human consumption. Intensification of shrimp farming had led to the development of a number of diseases, which resulted in the excessive use of antimicrobial agents, which is finally responsible for many adverse effects. Currently, probiotics are chosen as the best alternatives to these antimicrobial agents and they act as natural immune enhancers, which provoke the disease resistance in shrimp farm. Viral diseases stand as the major constraint causing an enormous loss in the production in shrimp farms. Probiotics besides being beneficial bacteria also possess antiviral activity. Exploitation of these probiotics in treatment and prevention of viral diseases in shrimp aquaculture is a novel and efficient method. This review discusses the benefits of probiotics and their criteria for selection in shrimp aquaculture and their role in immune power enhancement towards viral diseases.

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          Probiotic bacteria as biological control agents in aquaculture.

          There is an urgent need in aquaculture to develop microbial control strategies, since disease outbreaks are recognized as important constraints to aquaculture production and trade and since the development of antibiotic resistance has become a matter of growing concern. One of the alternatives to antimicrobials in disease control could be the use of probiotic bacteria as microbial control agents. This review describes the state of the art of probiotic research in the culture of fish, crustaceans, mollusks, and live food, with an evaluation of the results obtained so far. A new definition of probiotics, also applicable to aquatic environments, is proposed, and a detailed description is given of their possible modes of action, i.e., production of compounds that are inhibitory toward pathogens, competition with harmful microorganisms for nutrients and energy, competition with deleterious species for adhesion sites, enhancement of the immune response of the animal, improvement of water quality, and interaction with phytoplankton. A rationale is proposed for the multistep and multidisciplinary process required for the development of effective and safe probiotics for commercial application in aquaculture. Finally, directions for further research are discussed.
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            Cell-mediated immunity in arthropods: hematopoiesis, coagulation, melanization and opsonization.

            The functions of hemocytes in innate immune response are reviewed with emphasized on their roles in coagulation, melanization and opsonization. Also the ways in which hemocytes are produced in and released from hematopoietic tissue are discussed.
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              Overview of gut flora and probiotics

              Scientific developments in recent years have opened new frontiers and enable a better understanding of the gastrointestinal tract (GIT) as a complex and delicately balanced ecosystem. This paper focuses on more recent information related to the microbial population of the GIT and its functional role in human physiology and health. Special attention is also given to modern approaches for improving or stabilising the intestinal system and its functioning by the deliberate application of viable microbial cultures, so-called 'probiotics', selected for special functional properties.
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                Author and article information

                Journal
                J Pathog
                J Pathog
                JPATH
                Journal of Pathogens
                Hindawi Publishing Corporation
                2090-3057
                2090-3065
                2013
                30 April 2013
                : 2013
                : 424123
                Affiliations
                Department of Virology, Sri Venkateswara University, Tirupati 517502, India
                Author notes
                *D. V. R. Sai Gopal: dvrsaigopal@ 123456gmail.com

                Academic Editor: Cormac G. M. Gahan

                Author information
                https://orcid.org/0000-0002-9163-103X
                Article
                10.1155/2013/424123
                3657448
                23738078
                68fbf0da-3721-427c-82c9-06a2c60db3e8
                Copyright © 2013 Bestha Lakshmi et al.

                This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 24 February 2013
                : 9 April 2013
                Categories
                Review Article

                Infectious disease & Microbiology
                Infectious disease & Microbiology

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