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Basal and bevacizumab-based therapy-induced changes of lactate dehydrogenases and fibrinogen levels and clinical outcome of previously untreated metastatic colorectal cancer patients: a multicentric retrospective analysis.
Nicola Silvestris
1 ,
Mario Scartozzi ,
Giusi Graziano ,
Daniele Santini ,
Vito Lorusso ,
Evaristo Maiello ,
Sandro Barni ,
Saverio Cinieri ,
Fotios Loupakis ,
Salvatore Pisconti ,
Anna Elisabetta Brunetti ,
Giuseppe Palasciano ,
Vincenzo Ostilio Palmieri ,
Michela Del Prete ,
Emanuela Dell'Aquila ,
Tiziana Pia Latiano ,
Fausto Petrelli ,
Stefania Lutrino ,
Daniele Rossini ,
Riccardo Giampieri ,
Claudio Lotesoriere ,
Stefano Cascinu
Feb 2015
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Abstract
To assess the predictive role of lactate dehydrogenases (LDH) and fibrinogen (FBG) serum levels in metastatic colorectal cancer (mCRC) patients receiving a first-line bevacizumab-based therapy.