CYP3A5 *1 allele associated with tacrolimus trough concentrations but not subclinical acute rejection or chronic allograft nephropathy in Japanese renal transplant recipients.

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Abstract

We assessed reported associations of CYP3A5 *1 allele with a delay in achieving target tacrolimus concentrations, and occurrence of biopsy-confirmed subclinical acute rejection (SAR) and chronic allograft nephropathy (CAN) in Japanese subjects.

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Journal

Journal ID (iso-abbrev): Eur. J. Clin. Pharmacol.

Title: European journal of clinical pharmacology

Publisher: Springer Nature

ISSN (Electronic): 1432-1041

ISSN (Print): 0031-6970

Publication date (Electronic): May 2009

Volume: 65

Issue: 5

Affiliations

[1 ] Division of Renal Replacement Therapeutic Science, Department of Urology, Akita University School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan. shigerus@doc.med.akita-u.ac.jp

Article

DOI: 10.1007/s00228-008-0606-3

PubMed ID: 19125240

SO-VID: 697610cb-3fbd-4ff2-929d-f6ea64be2604

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