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      A Public Health Strategy for the Opioid Crisis

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          Abstract

          <p class="first" id="d454878e230">Drug overdose is now the leading cause of injury death in the United States. Most overdose fatalities involve opioids, which include prescription medication, heroin, and illicit fentanyl. Current data reveal that the overdose crisis affects all demographic groups and that overdose rates are now rising most rapidly among African Americans. We provide a public health perspective that can be used to mobilize a comprehensive local, state, and national response to the opioid crisis. We argue that framing the crisis from a public health perspective requires considering the interaction of multiple determinants, including structural factors (eg, poverty and racism), the inadequate management of pain, and poor access to addiction treatment and harm-reduction services (eg, syringe services). We propose a novel ecological framework for harmful opioid use that provides multiple recommendations to improve public health and clinical practice, including improved data collection to guide resource allocation, steps to increase safer prescribing, stigma-reduction campaigns, increased spending on harm reduction and treatment, criminal justice policy reform, and regulatory changes related to controlled substances. Focusing on these opportunities provides the greatest chance of making a measured and sustained impact on overdose and related harms. </p>

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          Most cited references54

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          Emergency department-initiated buprenorphine/naloxone treatment for opioid dependence: a randomized clinical trial.

          Opioid-dependent patients often use the emergency department (ED) for medical care.
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            Increases in Acute Hepatitis C Virus Infection Related to a Growing Opioid Epidemic and Associated Injection Drug Use, United States, 2004 to 2014

            To compare US trends in rates of injection drug use (IDU), specifically opioid injection, with national trends in the incidence of acute HCV infection to assess whether these events correlated over time.
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              Mortality after prison release: opioid overdose and other causes of death, risk factors, and time trends from 1999 to 2009.

              Among former prisoners, a high rate of death has been documented in the early postrelease period, particularly from drug-related causes. Little is known about risk factors and trends in postrelease mortality in the past decade, especially given general population increases in overdose deaths from pharmaceutical opioids. To determine postrelease mortality between 1999 and 2009; cause-specific mortality rates; and whether sex, calendar year, and custody factors were risk factors for all-cause, overdose, and opioid-related deaths. Cohort study. Prison system of the Washington State Department of Corrections. 76 208 persons released from prison. Identities were linked probabilistically to the National Death Index to identify deaths and causes of death, and mortality rates were calculated. Cox proportional hazards regression estimated the effect of age, sex, race or ethnicity, whether the incarceration resulted from a violation of terms of the person's community supervision, length of incarceration, release type, and calendar year on the hazard ratio (HR) for death. The all-cause mortality rate was 737 per 100 000 person-years (95% CI, 708 to 766) (n = 2462 deaths). Opioids were involved in 14.8% of all deaths. Overdose was the leading cause of death (167 per 100 000 person-years [CI, 153 to 181]), and overdose deaths in former prisoners accounted for 8.3% of the overdose deaths among persons aged 15 to 84 years in Washington from 2000 to 2009. Women were at increased risk for overdose (HR, 1.38 [CI, 1.12 to 1.69]) and opioid-related deaths (HR, 1.39 [CI, 1.09 to 1.79]). The study was done in only 1 state. Innovation is needed to reduce the risk for overdose among former prisoners. National Institute on Drug Abuse and the Robert Wood Johnson Foundation.
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                Author and article information

                Journal
                Public Health Reports
                Public Health Rep
                SAGE Publications
                0033-3549
                1468-2877
                November 14 2018
                November 2018
                November 14 2018
                November 2018
                : 133
                : 1_suppl
                : 24S-34S
                Affiliations
                [1 ]Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
                [2 ]School of Law and the Bouvé College of Health Sciences, Northeastern University, Boston, MA, USA
                [3 ]School of Medicine, University of California, San Diego, La Jolla, CA, USA
                [4 ]Department of Preventive Medicine and the Institute for Prevention Research at the Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
                [5 ]Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
                [6 ]Grayken Center for Addiction at Boston Medical Center, Boston, MA, USA
                [7 ]Department of Health, Behavior, and Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
                Article
                10.1177/0033354918793627
                6243441
                30426871
                69a7c546-a104-478c-9168-3bba898f0542
                © 2018

                http://journals.sagepub.com/page/policies/text-and-data-mining-license

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