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      Enteritis eosinofílica. A propósito de dos casos Translated title: Eosinophilic enteritis. Apropos of two cases

      case-report

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          Abstract

          Introducción: la enteritis eosinofílica transmural representa una entidad muy poco frecuente en Cuba, habiéndose reportado dos casos secundarios a infecciones parasitarias y uno primario publicado por Amores y col en el año 2009. Presentación de casos: se presentó dos pacientes que fueron llevados al quirófano con diagnóstico de úlcera péptica perforada y obstrucción intestinal, que al ser analizada la pieza histológica, se confirmó la presencia de enteritis eosinofílica con afección de todo el espesor de la pared intestinal. Discusión: aunque estas enfermedades son idiopáticas, recientes investigaciones apoyan el papel de los eosinofilos, las células auxiliadoras T 2 (Th2), las interleuquinas [IL]-3, IL-4, IL-5, e IL-13), y eotaxin como factores críticos en la patogénesis de la misma. Conclusiones: la enteritis eosinofílica es una entidad nosológica, que aunque catalogada como rara, lleva a frecuentes complicaciones quirúrgicas, y debe tenerse en cuenta en estos pacientes.

          Translated abstract

          Introduction: transmural eosinophilic enteritis represents an infrequent entity in Cuba, being reported only two cases secondary to parasitic infections and one primary, published by Amores et al in 2009. Case presentation: we present two patients that were taken to the operating room with the diagnosis of perforated peptic ulcer and intestinal obstruction, confirming the presence of eosinophilic enteritis with all of the intestinal wall thickness damaged when analyzing the histological piece. Discussion: although these diseases are idiopathic, recent research support the paper of eosinophils, T 2 helper cells (Th2), [IL]-3, IL-4, IL-5, and IL-13 interleukins, and eotaxin as critical factors in this disease pathogenesis. Conclusions: the eosinophilic enteritis is a nosocomial entity that although classified as rare, leads to frequent surgical complications, and should be kept in mind when treating these patients.

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          Most cited references17

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          Eosinophilic esophagitis: pathogenesis, genetics, and therapy.

          Eosinophilic esophagitis (EE) is a recently recognized disorder characterized by the accumulation of eosinophils in the esophagus. Symptoms of EE frequently mimic those of gastroesophageal reflux disease, but the 2 diseases are quite distinct in terms of the histopathology and response to therapy. We demonstrate that EE involves the interplay of numerous genes, especially the eosinophil chemoattractant eotaxin-3, allowing molecular distinction from other forms of esophagitis and consideration of targeted therapeutic intervention.
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            Eosinophilic gastroenteritis: clinical manifestations and morphological characteristics, a retrospective study of 42 patients.

            To evaluate the clinical manifestations, endoscopic, and radiological characteristics, histological features, and treatment of eosinophilic gastroenteritis in adult patients.
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              Gastrointestinal eosinophilia.

              Gastrointestinal eosinophilia, a broad term for abnormal eosinophil accumulation in the gastrointestinal tract, involves many different disease identities. These diseases include primary eosinophil associated gastrointestinal diseases, gastrointestinal eosinophilia in hypereosinophilic syndrome, and all gastrointestinal eosinophilic states associated with known causes. Each of these diseases has its unique features but there is no absolute boundary between them. All three groups of gastrointestinal eosinophila are described in this article, although the focus is on primary gastrointestinal eosinophilia.
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                Author and article information

                Journal
                rme
                Revista Médica Electrónica
                Rev.Med.Electrón.
                Universidad de Ciencias Médicas de Matanzas (Matanzas, , Cuba )
                1684-1824
                June 2014
                : 36
                : 3
                : 350-357
                Affiliations
                [01] Camagüey orgnameHospital Clínico Quirúrgico Docente Amalia Simoni Cuba
                Article
                S1684-18242014000300011 S1684-1824(14)03600311
                6a167dbf-e529-461b-abc9-b2db1a7b3307

                This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

                History
                : 01 April 2014
                : 28 April 2014
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 12, Pages: 8
                Product

                SciELO Cuba

                Self URI: Texto completo solamente en formato PDF (ES)
                Categories
                PRESENTACIÓN DE CASOS

                abdomen agudo,enteritis eosinofílica,eosinófilos,acute abdomen,eosinophilic enteritis,eosinophils

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