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      How inhibition shapes cortical activity.

      1 ,
      Neuron
      Elsevier BV

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          Abstract

          Cortical processing reflects the interplay of synaptic excitation and synaptic inhibition. Rapidly accumulating evidence is highlighting the crucial role of inhibition in shaping spontaneous and sensory-evoked cortical activity and thus underscores how a better knowledge of inhibitory circuits is necessary for our understanding of cortical function. We discuss current views of how inhibition regulates the function of cortical neurons and point to a number of important open questions.

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          Author and article information

          Journal
          Neuron
          Neuron
          Elsevier BV
          1097-4199
          0896-6273
          Oct 20 2011
          : 72
          : 2
          Affiliations
          [1 ] Center for Neural Circuits and Behavior, University of California San Diego, La Jolla, CA 92093-0634, USA. jisaacson@ucsd.edu
          Article
          NIHMS331929 S0896-6273(11)00879-8
          10.1016/j.neuron.2011.09.027
          3236361
          22017986
          6a3d8fc7-3425-4ec4-b6fa-8e45eff3b75d
          Copyright © 2011 Elsevier Inc. All rights reserved.
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