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      Treatment of aggressive lymphomas with anti-CD19 CAR T cells

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          Abstract

          <p class="first" id="P1">Adoptive immunotherapy using T cells genetically engineered to express a chimeric antigen receptor that targets CD19, a B-cell differentiation antigen, has demonstrated impressive efficacy in a range of B-lymphoid malignancies. The latest results demonstrate the potential of this approach in patients with chemotherapy-refractory diffuse large B-cell lymphoma. </p>

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          Author and article information

          Journal
          Nature Reviews Clinical Oncology
          Nat Rev Clin Oncol
          Springer Science and Business Media LLC
          1759-4774
          1759-4782
          December 2014
          November 11 2014
          December 2014
          : 11
          : 12
          : 685-686
          Article
          10.1038/nrclinonc.2014.190
          6327311
          25384948
          6a5d80f2-3437-4d5f-aa8d-c76f66b3faa3
          © 2014

          http://www.springer.com/tdm

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