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Abstract
The measurement of cortisol in saliva provides the basic scientist as well as the
clinician with a reliable tool for investigations of hypothalamus-pituitary-adrenal
axis activity. Since saliva samples can be obtained stress-free and independent from
medically trained personnel this method may be well suited for use in psychobiological
studies. This overview intends to give a comprehensive introduction to the method
of salivary cortisol assessment and to briefly discuss its application in different
scientific disciplines.