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      Registrando el protocolo de investigación Translated title: Registering the research protocol

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          PROSPERO: An International Register of Systematic Review Protocols.

          PROSPERO is an international database of systematic review protocols produced by the University of York's Center for Research and Dissemination and funded by the National Institute for Health Research. It contains protocols of systematic reviews on health and social care, welfare, public health, education, crime, justice, and health-related international development. PROSPERO compiles a comprehensive listing of systematic review protocols in an attempt to avoid duplication of effort, reduce reporting bias, and promote transparency.
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            Registration of systematic reviews in PROSPERO: 30,000 records and counting

            Background The International Prospective Register of Systematic Reviews (PROSPERO) was launched in February 2011 to increase transparency of systematic reviews (SRs). There have been few investigations of the content and use of the database. We aimed to investigate the number of PROSPERO registrations from inception to 2017, and website usage in the last year. We also aimed to explore the epidemiological characteristics of and completeness of primary outcome pre-specification in a sample of PROSPERO records from 2017. Methods The PROSPERO database managers provided us with data on the annual and cumulative number of SR registrations up to October 10, 2017, and the number of visits to the PROSPERO website over the year preceding October 10, 2017. One author collected data on the focus of the SR (e.g. therapeutic, diagnostic), health area addressed, funding source and completeness of outcome pre-specification in a random sample of 150 records of SRs registered in PROSPERO between April 1, 2017 and September 30, 2017. Results As of October 10, 2017, there were 26,535 SRs registered in PROSPERO; guided by current monthly submission rates, we anticipate this figure will reach over 30,000 by the end of 2017. There has been a 10-fold increase in registrations, from 63 SRs per month in 2012 to 800 per month in 2017. In the year preceding October 10, 2017, the PROSPERO website received more than 1.75 million page views. In the random sample of 150 registered SRs, the majority were focused on a therapeutic question (78/150 [52%]), while only a few focused on a diagnostic/prognostic question (11/150 [7%]). The 150 registered SRs addressed 18 different health areas. Any information about the primary outcome other than the domain (e.g. timing, effect measures) was not pre-specified in 44/150 records (29%). Conclusions Registration of SRs in PROSPERO increased rapidly between 2011 and 2017, thus benefiting users of health evidence who want to know about ongoing SRs. Further work is needed to explore how closely published SRs adhere to the planned methods, whether greater pre-specification of outcomes prevents selective inclusion and reporting of study results, and whether registered SRs address necessary questions.
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              Registration in the international prospective register of systematic reviews (PROSPERO) of systematic review protocols was associated with increased review quality

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                Author and article information

                Journal
                nh
                Nutrición Hospitalaria
                Nutr. Hosp.
                Grupo Arán (Madrid, Madrid, Spain )
                0212-1611
                1699-5198
                June 2023
                : 40
                : 3
                : 668-669
                Affiliations
                [1] Concepción Bío-Bío orgnameUniversidad Católica de la Santísima Concepción orgdiv1Facultad de Medicina orgdiv2Departamento de Salud Pública Chile
                [2] Concepción Bío-Bío orgnameUniversidad Católica de la Santísima Concepción orgdiv1Facultad de Medicina orgdiv2Departamento de Ciencias Clínicas y Preclínicas Chile
                [5] Santiago Santiago de Chile orgnameUniversidad de Las Américas orgdiv1Facultad de Salud y Ciencias Sociales Chile
                [3] Concepción orgnameUniversidad Andrés Bello orgdiv1Facultad de Odontología orgdiv2Escuela de Odontología Chile
                [4] Santiago orgnameUniversidad Central de Chile orgdiv1Facultad de Educación y Ciencias Sociales Chile
                Article
                S0212-16112023000400027 S0212-1611(23)04000300027
                10.20960/nh.04615
                6aafadfa-7cb8-4a01-afa3-5ce1f1c045ff

                This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

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