24
views
0
recommends
+1 Recommend
1 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Birth cohort differences in the use of medications in a Brazilian population of older elderly: the Bambuí cohort study of aging (1997 and 2008) Translated title: Diferenças de coorte por nascimento no uso de medicamentos em uma população Brasileira de idosos mais velhos: estudo de coorte de idosos de Bambuí (1997 e 2008)

      research-article

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          This study examined differences in the use of medications in two birth cohorts (born from 1916 to 1926 and from 1927 to 1937) among older elderly in the population-based cohort study in Bambuí, Minas Gerais State, Brazil. The study used data on participants who were 71-81 years of age in the baseline survey in 1997 (n = 492) and in the 11th wave, in 2008 (n = 620). The number of medications currently consumed (mean = 4.6 and 3.4, respectively) and prevalence of polypharmacy (46.6% and 29.1%, respectively) were higher in the more recent cohort as compared to the earlier one. These differences were independent of gender, age, schooling, number of medical visits in the previous 12 months, and number of chronic conditions. The more recent cohort showed significant differences in the use of psychoactive drugs, lipid modifying agents, drugs for diabetes, and antithrombotic agents, as well as changes in drugs used for arterial hypertension. In general, these changes are consistent with those observed in elderly populations in high-income countries.

          Translated abstract

          Foram examinadas diferenças de coorte (entre nascidos em 1916-1926 e em 1927-1937) no uso de medicamentos entre idosos participantes do Estudo de Coorte de Idosos de Bambuí. Foram utilizados dados dos participantes com 71-81 anos de idade da linha de base em 1997 (n = 492) e do 11º ano de seguimento em 2008 (n = 620). O número de medicamentos consumidos (média = 4,6 e 3,4, respectivamente) e a prevalência da polifarmácia (46,6% e 29,1%, respectivamente) foram mais altos na coorte recente, em comparação à antiga. Essas diferenças foram independentes do sexo, idade, escolaridade, número de consultas médicas e número de doenças crônicas. Na coorte mais jovem, observaram-se aumentos significativos no uso de psicofármacos, agentes modificadores de lipídios, hipoglicemiantes e antitrombóticos, assim como mudanças nos medicamentos utilizados para o controle da hipertensão arterial. De maneira geral, essas mudanças são consistentes com o observado em populações idosas de países de alta renda.

          Related collections

          Most cited references94

          • Record: found
          • Abstract: not found
          • Article: not found

          Recent Patterns of Medication Use in the Ambulatory Adult Population of the United States

            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Use of medications and polypharmacy are increasing among the elderly.

            To assess changes in medicine use and polypharmacy, two cross-sectional surveys were carried out among community-dwelling persons aged 64 years or over in 1990-91 (n = 1,131) and 1998-99 (n = 1,197) in the municipality of Lieto in southwestern Finland. In addition to drug use, the questionnaire included items on social background, quality of life, and home nursing services. Among those surveyed, 78% in 1990-1991 and 88% in 1998-1999 (P =.001) used prescription drugs during 7 days prior to the interview. The most commonly used medications were for the cardiovascular and central nervous systems. The number of medications per person increased from 3.1 (SD 2.8) to 3.8 (SD 3.1) (P =.0001), and polypharmacy (concominant use of over five medications) increased from 19 to 25% (P =.006). These changes were most prominent among persons aged 85 years or over, especially among women. Polypharmacy is a complex and worrying phenomenon that merits more research.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Primary prevention of ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council: cosponsored by the Atherosclerotic Peripheral Vascular Disease Interdisciplinary Working Group; Cardiovascular Nursing Council; Clinical Cardiology Council; Nutrition, Physical Activity, and Metabolism Council; and the Quality of Care and Outcomes Research Interdisciplinary Working Group.

              This guideline provides an overview of the evidence on various established and potential stroke risk factors and provides recommendations for the reduction of stroke risk. Writing group members were nominated by the committee chair on the basis of each writer's previous work in relevant topic areas and were approved by the American Heart Association Stroke Council's Scientific Statement Oversight Committee. The writers used systematic literature reviews (covering the time period since the last review published in 2001 up to January 2005), reference to previously published guidelines, personal files, and expert opinion to summarize existing evidence, indicate gaps in current knowledge, and when appropriate, formulate recommendations based on standard American Heart Association criteria. All members of the writing group had numerous opportunities to comment in writing on the recommendations and approved the final version of this document. The guideline underwent extensive peer review before consideration and approval by the AHA Science Advisory and Coordinating Committee. Schemes for assessing a person's risk of a first stroke were evaluated. Risk factors or risk markers for a first stroke were classified according to their potential for modification (nonmodifiable, modifiable, or potentially modifiable) and strength of evidence (well documented or less well documented). Nonmodifiable risk factors include age, sex, low birth weight, race/ethnicity, and genetic factors. Well-documented and modifiable risk factors include hypertension, exposure to cigarette smoke, diabetes, atrial fibrillation and certain other cardiac conditions, dyslipidemia, carotid artery stenosis, sickle cell disease, postmenopausal hormone therapy, poor diet, physical inactivity, and obesity and body fat distribution. Less well-documented or potentially modifiable risk factors include the metabolic syndrome, alcohol abuse, drug abuse, oral contraceptive use, sleep-disordered breathing, migraine headache, hyperhomocysteinemia, elevated lipoprotein(a), elevated lipoprotein-associated phospholipase, hypercoagulability, inflammation, and infection. Data on the use of aspirin for primary stroke prevention are reviewed. Extensive evidence is available identifying a variety of specific factors that increase the risk of a first stroke and providing strategies for reducing that risk.
                Bookmark

                Author and article information

                Contributors
                Role: ND
                Role: ND
                Role: ND
                Role: ND
                Journal
                csp
                Cadernos de Saúde Pública
                Cad. Saúde Pública
                Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz (Rio de Janeiro )
                1678-4464
                2011
                : 27
                : suppl 3
                : s435-s443
                Affiliations
                [1 ] Fundação Oswaldo Cruz Brazil
                [2 ] Universidade Federal de Minas Gerais Brazil
                [3 ] Universidade Federal de Minas Gerais Brazil
                Article
                S0102-311X2011001500014
                10.1590/S0102-311X2011001500014
                21952865
                6ad3a473-bb60-4480-9f8e-f7e7f6de4c5d

                http://creativecommons.org/licenses/by/4.0/

                History
                Product

                SciELO Brazil

                Self URI (journal page): http://www.scielosp.org/scielo.php?script=sci_serial&pid=0102-311X&lng=en
                Categories
                Health Policy & Services

                Public health
                Drug Utilization,Aged,Cohort Studies,Uso de Medicamentos,Idoso,Estudos de Coortes
                Public health
                Drug Utilization, Aged, Cohort Studies, Uso de Medicamentos, Idoso, Estudos de Coortes

                Comments

                Comment on this article