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      The validity of Salvadoria persica and Nigella sativa in the treatment of dry socket Translated title: La validez de Salvadoria persica y Nigella sativa en el tratamiento de la alveolitis seca

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          Abstract

          ABSTRACT Objectives: To evaluate the effectiveness of a mixture of Salvadoria persica and Nigella sativa in treating dry socket and use as a substitute for alvogyl. Patients and method: 52 randomly selected patients with dry socket confirmed clinically by diagnosis, divided into 2 groups, each group containing 26 patient group A treated by admix, and group B treated by alvogyl, clinical features were recorded on the first, second, and third days after treatment. Results: Visual Analog Scale of pain showed a high score on day one but decreased significantly at 2 and 3 days in both groups. But there were no significant differences in pain scores between the two groups on day 1, day 2, or day 3 separately. The two groups revealed identical mean rank scores of pain during the whole study period. Conclusions: A mixture of Salvadoria persica and Nigella sativa showed a significant analgesic and anti-inflammatory effect in the treatment of dry socket and can be used as a substitute for alvogyl.

          Translated abstract

          RESUMEN Objetivos: Evaluar la eficacia de una mezcla de Salvadoria persica y Nigella sativa en el tratamiento de la alveolitis seca y su uso como sustituto del alvogyl. Pacientes y método: 52 pacientes seleccionados al azar con alveolitis seca confirmada clínicamente por diagnóstico, divididos en 2 grupos, cada grupo con 26 pacientes del grupo A tratado con admix y del grupo B tratado con alvogyl. Las características clínicas se registraron al primer, segundo y tercer día después del tratamiento. Resultados: La escala analógica visual del dolor mostró una puntuación alta el primer día, pero disminuyó significativamente a los 2 y 3 días en ambos grupos. No hubo diferencias significativas en las puntuaciones de dolor entre los 2 grupos los días 1, 2 y 3 por separado. Los dos grupos revelaron las mismas puntuaciones medias de rango de dolor durante todo el periodo de estudio. Conclusiones: Una mezcla de Salvadoria persica y Nigella sativa mostró un efecto analgésico y antinflamatorio significativo en el tratamiento de la alveolitis seca y puede utilizarse como sustituto del alvogyl.

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          Most cited references24

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          A review on therapeutic potential of Nigella sativa: A miracle herb.

          Nigella sativa (N. sativa) (Family Ranunculaceae) is a widely used medicinal plant throughout the world. It is very popular in various traditional systems of medicine like Unani and Tibb, Ayurveda and Siddha. Seeds and oil have a long history of folklore usage in various systems of medicines and food. The seeds of N. sativa have been widely used in the treatment of different diseases and ailments. In Islamic literature, it is considered as one of the greatest forms of healing medicine. It has been recommended for using on regular basis in Tibb-e-Nabwi (Prophetic Medicine). It has been widely used as antihypertensive, liver tonics, diuretics, digestive, anti-diarrheal, appetite stimulant, analgesics, anti-bacterial and in skin disorders. Extensive studies on N. sativa have been carried out by various researchers and a wide spectrum of its pharmacological actions have been explored which may include antidiabetic, anticancer, immunomodulator, analgesic, antimicrobial, anti-inflammatory, spasmolytic, bronchodilator, hepato-protective, renal protective, gastro-protective, antioxidant properties, etc. Due to its miraculous power of healing, N. sativa has got the place among the top ranked evidence based herbal medicines. This is also revealed that most of the therapeutic properties of this plant are due to the presence of thymoquinone which is major bioactive component of the essential oil. The present review is an effort to provide a detailed survey of the literature on scientific researches of pharmacognostical characteristics, chemical composition and pharmacological activities of the seeds of this plant.
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            Contemporary views on dry socket (alveolar osteitis): a clinical appraisal of standardization, aetiopathogenesis and management: a critical review.

            I Blum (2002)
            The objective of this article is to harmonize descriptive definitions for the condition known as alveolar osteitis and to critically review and discuss the aetiology and pathogenesis of alveolar osteitis. In addition, the need for the identification and elimination of risk factors as well as the preventive and symptomatic management of the condition are discussed. The aim of this critical review is to provide a better basis for clinical management of the condition. A meta-analysis of data was not done.
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              The anti-inflammatory, analgesic and antipyretic activity of Nigella sativa.

              The aqueous extract of Nigella sativa (N. sativa) was investigated for anti-inflammatory, analgesic and antipyretic activities in animal models. The extract has an anti-inflammatory effect demonstrated by its inhibitory effects on Carrageenan induced paw edema. It also produced significant increase in the hot plate reaction time in mice indicating analgesic effect. However, N. sativa crude suspension had no effect on yeast induced pyrexia. This study therefore, supports its use in folk medicine both as analgesic and anti-inflammatory agent and calls for further investigations to elucidate its mechanism of action.
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                Author and article information

                Journal
                maxi
                Revista Española de Cirugía Oral y Maxilofacial
                Rev Esp Cirug Oral y Maxilofac
                Sociedad Española de Cirugía Oral y Maxilofacial y de Cabeza y Cuello (Madrid, Madrid, Spain )
                1130-0558
                2173-9161
                September 2022
                : 44
                : 3
                : 100-104
                Affiliations
                [1] Mosul orgnameMosul University orgdiv1Dentistry College orgdiv2Oral and Maxillofacial Surgery Department Iraq
                [2] Mosul orgnameMosul University orgdiv1Dentistry College orgdiv2Dental Basic Sciences Department Iraq
                Article
                S1130-05582022000300002 S1130-0558(22)04400300002
                10.20986/recom.2022.1368/2022
                6ae674ba-4122-4e9d-a5f1-61b8f46ee9f3

                This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

                History
                : 18 May 2022
                : 16 July 2022
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 24, Pages: 5
                Product

                SciELO Spain

                Categories
                Originals

                Nigella sativa,Salvadoria persica,Dry socket treatment,Tratamiento de alvéolo seco

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