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      Instrumentation for the measurement of electric brain responses to transcranial magnetic stimulation.

      Medical & Biological Engineering & Computing
      Electrodes, Equipment Design, Humans, Magnetoencephalography, instrumentation

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          Abstract

          There is described a 60-channel EEG acquisition system designed for the recording of scalp-potential distributions starting just 2.5 ms after individual transcranial magnetic stimulation (TMS) pulses. The amplifier comprises gain-control and sample-and-hold circuits to prevent large artefacts from magnetically induced voltages in the leads. The maximum amplitude of the stimulus artefact during the 2.5 ms gating period is 1.7 microV, and 5 ms after the TMS pulse it is only 0.9 microV. It is also shown that mechanical forces to the electrodes under the stimulator coil are a potential source of artefacts, even though, with chlorided silver wire and Ag/AgCl-pellet electrodes, the artefact is smaller than 1 microV. The TMS-compatible multichannel EEG system makes it possible to locate TMS-evoked electric activity in the brain.

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          Author and article information

          Journal
          10505382
          10.1007/BF02513307

          Chemistry
          Electrodes,Equipment Design,Humans,Magnetoencephalography,instrumentation
          Chemistry
          Electrodes, Equipment Design, Humans, Magnetoencephalography, instrumentation

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