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      Mature Cystic Renal Teratoma

      case-report

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          Abstract

          Teratomas are rare germline tumors that originate from one or more embryonic germ cell layers. Teratoma of the kidney is extremely rare, and less than 30 cases of primary intrarenal teratomas have been published to date. We report the main radiologic features of an unusual case of mature cystic teratoma arising from the left kidney in a two-year-old boy. A left-sided abdominal mass was detected on physical examination and B-Mod Ultrasound (US) examination revealed a heterogeneous mass with central cystic component. Computed tomography (CT) demonstrated a lobulated, heterogeneous, hypodense mass extending craniocaudally from the splenic hilum to the level of the left iliac fossa. Nephrectomy was performed and a large, fatty mass arising from the left kidney was excised. The final pathologic diagnosis was confirmed as cystic renal teratoma.

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          Most cited references13

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          Wilms' tumor and other renal tumors of childhood: a selective review from the National Wilms' Tumor Study Pathology Center.

          Selected studies of Wilms' tumor and related renal neoplasms in children, which have been based on the National Wilms' Tumor Study Pathology Center collection of more than 2,600 renal tumors of childhood, are reviewed. The purpose of the review is to illustrate the value of the collaborative approach to uncommon pathologic specimens and to distinguish several tumors often confused with Wilms' tumor, including renal adenocarcinoma, renal teratoma, and renal neurogenic tumors. The unfavorable prognostic significance of anaplastic cells in Wilms' tumor is emphasized. Two recently described clinicopathologic entities--clear cell sarcoma of kidney and malignant rhabdoid tumor of kidney--and morphologic variants often confused with Wilms' tumor or congenital mesoblastic nephroma of infancy are discussed. Clear cell sarcoma of kidney and malignant rhabdoid tumor of kidney are, apparently, distinctive neoplasms, not Wilms' tumor variants.
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            Primary carcinoid tumor arising in a mature teratoma of the kidney: a case report and review of the literature.

            Primary carcinoid tumor, especially that arising in a mature teratoma of the kidney, is extremely rare; only 3 cases have been reported in the world literature to date. Because of the rarity of the lesion, its histogenesis and prognosis are unknown. We report a case of primary renal carcinoid tumor occurring in a mature teratoma in a 30-year-old woman. A computed tomographic scan of the abdomen revealed a mass in the left kidney containing dense calcification with minimal contrast enhancement. Histologically, the tumor was composed of trabecular and anastomosing ribbonlike nests, identical to the features of carcinoid tumors of other sites. Immunohistochemical stainings were positive for cytokeratin, neuron-specific enolase, and chromogranin. In addition, there were mature teratoid tissues, such as columnar epithelium, smooth muscle, and bone. The carcinoid tumor was under and closely apposed to the lining of the cysts. The patient did not have clinical manifestations of the carcinoid syndrome and had an uneventful recovery.
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              Carcinoid tumor occurring in cystic teratoma of the kidney: a case report.

              Although carcinoid tumors have occurred rarely in benign teratomas of the ovary and the testis, we believe this case is the first reported of carcinoid arising in a benign cystic teratoma of the kidney. The patient was admitted to the Tagawa Hospital with a left abdominal mass and severe epigastric pain. Retrograde and intravenous pyelograms revealed marked dilatation of the left kidney; a renal tumor was diagnosed clinically. At operation, a polycystic tumor weighing 1400g was removed. Histologically, a carcinoid tumor was evident among teratoid tissues, such as columnar epithelium, cartilage, smooth muscle, and mucous secretory glands. The patient did not have a carcinoid syndrome and had an uneventful recovery.
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                Author and article information

                Journal
                Iran J Radiol
                Iran J Radiol
                10.5812/iranjradiol
                Kowsar
                Iranian Journal of Radiology
                Kowsar
                1735-1065
                2008-2711
                30 January 2014
                January 2014
                : 11
                : 1
                : e11260
                Affiliations
                [1 ]Department of Radiology, Yuzuncu Yil University Hospital, Ercis Yolu, Geve Kampus, Van, Turkey
                [2 ]Department of Radiology, Akdeniz University, Kampus Antalya, Turkey
                [3 ]Department of Pathology, Akdeniz University, Kampus Antalya, Turkey
                Author notes
                [* ]Corresponding author: Alpaslan Yavuz, Department of Radiology, Yuzuncu Yil University Hospital, Ercis Yolu, Geve Kampus, Van, Turkey. Tel: +90-5323424959, Fax: +90-4322168352, E-mail: dralpyavuz@ 123456hotmail.com
                Article
                10.5812/iranjradiol.11260
                3955850
                6b50a603-b92e-4b98-b035-7cda798bcdcd
                Copyright © 2014, Tehran University of Medical Sciences and Iranian Society of Radiology; Published by Kowsar Corp.

                This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 19 March 2013
                : 15 April 2013
                : 06 May 2013
                Categories
                Urogenital Imaging & Contrast Media

                Radiology & Imaging
                teratoma,ultrasound,computed tomography,cystic,kidney
                Radiology & Imaging
                teratoma, ultrasound, computed tomography, cystic, kidney

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