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      Transfer of the Brachialis to the Anterior Interosseous Nerve as a Treatment Strategy for Cervical Spinal Cord Injury: Technical Note

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          Abstract

          Study Design Technical report.

          Objective To provide a technical description of the transfer of the brachialis to the anterior interosseous nerve (AIN) for the treatment of tetraplegia after a cervical spinal cord injury (SCI).

          Methods In this technical report, the authors present a case illustration of an ideal surgical candidate for a brachialis-to-AIN transfer: a 21-year-old patient with a complete C7 spinal cord injury and failure of any hand motor recovery. The authors provide detailed description including images and video showing how to perform the brachialis-to-AIN transfer.

          Results The brachialis nerve and AIN fascicles can be successfully isolated using visual inspection and motor mapping. Then, careful dissection and microsurgical coaptation can be used for a successful anterior interosseous reinnervation.

          Conclusion The nerve transfer techniques for reinnervation have been described predominantly for the treatment of brachial plexus injuries. The majority of the nerve transfer techniques have focused on the upper brachial plexus or distal nerves of the lower brachial plexus. More recently, nerve transfers have reemerged as a potential reinnervation strategy for select patients with cervical SCI. The brachialis-to-AIN transfer technique offers a potential means for restoration of intrinsic hand function in patients with SCI.

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          Most cited references42

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          Survey of the needs of patients with spinal cord injury: impact and priority for improvement in hand function in tetraplegics.

          To investigate the impact of upper extremity deficit in subjects with tetraplegia. The United Kingdom and The Netherlands. Survey among the members of the Dutch and UK Spinal Cord Injury (SCI) Associations. MAIN OUTCOME PARAMETER: Indication of expected improvement in quality of life (QOL) on a 5-point scale in relation to improvement in hand function and seven other SCI-related impairments. In all, 565 subjects with tetraplegia returned the questionnaire (overall response of 42%). Results in the Dutch and the UK group were comparable. A total of 77% of the tetraplegics expected an important or very important improvement in QOL if their hand function improved. This is comparable to their expectations with regard to improvement in bladder and bowel function. All other items were scored lower. This is the first study in which the impact of upper extremity impairment has been assessed in a large sample of tetraplegic subjects and compared to other SCI-related impairments that have a major impact on the life of subjects with SCI. The present study indicates a high impact as well as a high priority for improvement in hand function in tetraplegics.
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            Motor and sensory recovery following incomplete tetraplegia.

            Fifty individuals with incomplete tetraplegia due to trauma underwent serial prospective examinations to quantify motor and sensory recovery. None of 5 patients who were motor complete with the presence of sacral (S4-S5) sharp/dull touch sensation unilaterally recovered any lower extremity motor function. However, in 8 motor complete subjects having bilateral sacral sharp/dull sensation present, the mean lower extremity motor score increased to 12.1 +/- 7.8 at 1 year. In 3 of the 8 cases, functional (> or = 3/5) recovery was seen in some muscles at 1 year. Though mean upper and lower extremity ASIA Motor Scores increased significantly (p or = 10 at 1 month were community ambulators using crutches and orthoses at 1 year follow-up.
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              Combined nerve transfers for C5 and C6 brachial plexus avulsion injury.

              To report the results of combined nerve transfer in C5 and C6 brachial plexus avulsion injury. Fifteen patients had nerve transfers: spinal accessory nerve to the suprascapular nerve, a part of the ulnar nerve to the biceps motor branch, and the nerve to the long head of the triceps to the anterior branch of the axillary nerve. Patients were evaluated with regard to elbow flexion, shoulder abduction, and shoulder external rotation. All patients had recovered full elbow flexion: 13 scored M4 and 2 scored M3. Thirteen of the 15 patients obtained good results. The weight the patients could lift ranged from 0 to 7 kg. All patients had recovery of the deltoid function: 13 scored M4 and 2 scored M3. All 15 patients achieved useful functional recovery. Ten patients experienced excellent recoveries and 5 were classified as having good results. The mean shoulder abduction was 115 degrees . Shoulder external rotation strength was scored as M4 in 9 patients, M3 in 4 patients, and M2 in 2 patients. The range of motion of external rotation that was measured from full internal rotation averaged 97 degrees . No clinical donor nerve deficits were observed. We recommend combined nerve transfers for C5 and C6 avulsion root injuries. These nerve transfers have the advantage of a quick recovery time as a result of the short regeneration distance without nerve graft. Therapeutic, Level IV.
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                Author and article information

                Journal
                Global Spine J
                Global Spine J
                10.1055/s-00000177
                Global Spine Journal
                Georg Thieme Verlag KG (Stuttgart · New York )
                2192-5682
                2192-5690
                15 December 2014
                April 2015
                : 5
                : 2
                : 110-117
                Affiliations
                [1 ]Department of Neurosurgery, Washington University School of Medicine, St. Louis, Missouri, United States
                Author notes
                Address for correspondence Wilson Z. Ray, MD Department of Neurosurgery, Washington University School of Medicine 660 South Euclid Avenue, Campus Box 8057, St. Louis, MO 63110United States RayZ@ 123456wudosis.wustl.edu
                Article
                1400114
                10.1055/s-0034-1396760
                4369208
                25844283
                6b6fe5b6-6441-40f2-89e5-b25569251274
                © Thieme Medical Publishers
                History
                : 08 September 2014
                : 03 November 2014
                Categories
                Article

                brachialis,anterior interosseous nerve,nerve transfer,spinal cord injury

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