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      Local treatment of psoriasis of the scalp with clobetasol propionate and betamethasone-17,21-dipropionate: a double-blind comparison.

      Current medical research and opinion
      Informa Healthcare

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          Abstract

          A double-blind evaluation was carried out in 40 patients with moderate to severe psoriasis of the scalp to assess the effectiveness of a 0.05% alcoholic solution of clobetasol propionate as compared with a 0.05% alcoholic solution of betamethasone-17,21-dipropionate. Patients were treated on a non-selective basis with a twice a day application for 2 weeks. When comparing the effects on the parameters scaling, induration, erythema and itching it was concluded that clobetasol propionate was superior to betamethasone-17,21-dipropionate as an antipsoriatic compound. Clobetasol propionate did not cause any side-effects, while 2 of the patients using betamethasone-17,21-dipropionate developed a forehead folliculitis during the second week of treatment.

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          Author and article information

          Journal
          Curr Med Res Opin
          Current medical research and opinion
          Informa Healthcare
          0300-7995
          0300-7995
          1976
          : 4
          : 5
          Article
          10.1185/03007997609109330
          795609
          6c1a8d85-0dbe-4716-9d83-cdf867967995
          History

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