- Record: found
- Abstract: not found
- Article: not found
A daily rhythm in behavioral vasopressin sensitivity and brain vasopressin concentrations
July 1985
July 1985
Read this article at
There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.
Abstract
The concentration of Arg-vasopressin (AVP) in the suprachiasmatic nuclei of the hypothalamus
(SCN), the neural generator of circadian rhythms, showed a daily rhythm, which was
inversely related to the rhythm in lordosis, an aspect of sexual behavior shown by
ovariectomized estradiol-17 beta-treated female rats. A threshold dose of an AVP antagonist
facilitated sexual behavior most effectively if injected intracerebroventricularly
when the endogenous levels of AVP in the SCN were maximal and a threshold dose of
AVP inhibited the behavior most effectively if injected when these levels were minimal.
The results support the suggestion that AVP may be the neuropeptide whereby the SCN
generate some behavioral rhythms.